A Genetic Approach to the Association Between PCSK9 and Sepsis-Reference-Cited by-同舟云学术

A Genetic Approach to the Association Between PCSK9 and Sepsis

Published:2019-09-11 Issue:9 Volume:2 Page:e1911130
ISSN:2574-3805
Container-title:JAMA Network Open
language:en
Short-container-title:JAMA Netw Open

Author:

Feng QiPing¹,Wei Wei-Qi²,Chaugai Sandip¹,Carranza Leon Barbara G.³,Kawai Vivian¹,Carranza Leon Daniel A.¹,Jiang Lan¹,Zhong Xue⁴⁵,Liu Ge¹,Ihegword Andrea¹,Shaffer Christian M.¹,Linton MacRae F.⁶⁷,Chung Cecilia P.¹⁸,Stein C. Michael¹⁶

Affiliation:

1. Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

2. Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee

3. Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

4. Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

5. Vanderbilt Genetic Institute, Vanderbilt University, Nashville, Tennessee

6. Department of Pharmacology, Vanderbilt University, Nashville, Tennessee

7. Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

8. Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jamanetworkopen/article-pdf/2/9/e1911130/17860558/feng_2019_oi_190436.pdf

Reference45 articles.

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2. Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014.;Rhee;JAMA,2017

3. Severe sepsis and septic shock.;Angus;N Engl J Med,2013

4. PCSK9 is a critical regulator of the innate immune response and septic shock outcome.;Walley;Sci Transl Med,2014

5. PCSK9 inhibitors in sepsis: a new potential indication?;Momtazi;Expert Opin Investig Drugs,2017

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