Development and Validation of Machine Learning Models for Predicting Occult Nodal Metastasis in Early-Stage Oral Cavity Squamous Cell Carcinoma

Author:

Farrokhian Nathan1,Holcomb Andrew J.2,Dimon Erin1,Karadaghy Omar1,Ward Christina1,Whiteford Erin2,Tolan Claire2,Hanly Elyse K.3,Buchakjian Marisa R.3,Harding Brette4,Dooley Laura4,Shinn Justin5,Wood C. Burton5,Rohde Sarah L.5,Khaja Sobia6,Parikh Anuraag7,Bulbul Mustafa G.7,Penn Joseph1,Goodwin Sara1,Bur Andrés M.1

Affiliation:

1. Department of Otolaryngology–Head and Neck Surgery, University of Kansas Medical Center, Kansas City

2. Department of Otolaryngology, Nebraska Methodist Health System, Omaha

3. Department of Otolaryngology–Head and Neck Surgery, University of Iowa, Iowa City

4. Department of Otolaryngology–Head and Neck Surgery, University of Missouri, Columbia

5. Department of Otolaryngology–Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee

6. Department of Otolaryngology–Head and Neck Surgery, University of Minnesota, Minneapolis

7. Department of Otolaryngology–Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard University, Boston

Publisher

American Medical Association (AMA)

Subject

General Medicine

Reference49 articles.

1. Treatment of the N+ neck in squamous cell carcinoma of the upper aerodigestive tract.;Myers;Otolaryngol Clin North Am,1998

2. Cervical lymph node metastases—diagnostic, therapeutic, and prognostic implications.;Shah;Oncology (Williston Park),1990

3. Head and neck cancers, version 2.2020, NCCN clinical practice guidelines in oncology.;Pfister;J Natl Compr Canc Netw,2020

4. Elective versus therapeutic neck dissection in node-negative oral cancer.;D’Cruz;N Engl J Med,2015

5. Treatment of stage I and II oral tongue cancer.;Lydiatt;Head Neck,1993

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