Cost of Pacing in Pediatric Patients With Postoperative Heart Block After Congenital Heart Surgery

Author:

Mondal Abhijit12,Yoo Minkyoung3,Tuttle Stephanie1,Mah Douglas45,Nelson Richard3,Sachse Frank B.6,Hitchcock Robert6,Kaza Aditya K.12

Affiliation:

1. Department of Cardiac Surgery, Boston Children’s Hospital, Boston, Massachusetts

2. Department of Surgery, Harvard Medical School, Boston, Massachusetts

3. Division of Epidemiology, University of Utah, Salt Lake City

4. Department of Cardiology, Boston Children’s Hospital, Boston, Massachusetts

5. Department of Pediatrics, Harvard Medical School, Boston, Massachusetts

6. Department of Biomedical Engineering, University of Utah, Salt Lake City

Abstract

ImportanceSurgical correction of congenital heart defects (CHDs) has improved the lifespan and quality of life of pediatric patients. The number of congenital heart surgeries (CHSs) in children has grown continuously since the 1960s. This growth has been accompanied by a rise in the incidence of postoperative heart block requiring permanent pacemaker (PPM) implantation.ObjectiveTo assess the trends in permanent pacing after CHS and estimate the economic burden to patients and their families after PPM implantation.Design, Setting, and ParticipantsIn this economic evaluation study, procedure- and diagnosis-specific codes within a single-institution database were used to identify patients with postoperative heart block after CHS between January 1, 1960, and December 31, 2018. Patients younger than 4 years with postoperative PPM implantation were selected, and up to 20-year follow-up data were used for cost analysis based on mean hospital event charges and length of stay (LOS) data. Data were analyzed from January 1, 2020, to November 30, 2022.ExposureImplantation of PPM after CHS in pediatric patients.Main Outcomes and MeasuresAnnual trends in CHS and postoperative PPM implantations were assessed. Direct and indirect costs associated with managing conduction health for the 20 years after PPM implantation were estimated using Markov model simulation and patient follow-up data.ResultsOf the 28 225 patients who underwent CHS, 968 (437 female [45.1%] and 531 male [54.9%]; 468 patients aged <4 years) received a PPM due to postoperative heart block. The rate of CHS and postoperative PPM implantations increased by 2.2% and 7.2% per year between 1960 and 2018, respectively. In pediatric patients younger than 4 years with PPM implantation, the mean (SD) 20-year estimated direct and indirect costs from Markov model simulations were $180 664 ($32 662) and $15 939 ($1916), respectively. Using follow-up data of selected patients with clinical courses involving 1 or more complication events, the mean (SD) direct and indirect costs were $472 774 ($212 095) and $36 429 ($16 706), respectively.Conclusions and RelevanceIn this economic evaluation study, the cost of PPM implantation in pediatric patients was found to accumulate over the lifespan. This cost may represent not only a substantial financial burden but also a health care burden to patient families. Reducing the incidence of PPM implantation should be a focused goal of CHS.

Publisher

American Medical Association (AMA)

Subject

General Medicine

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