Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer

Author:

Burzykowski Tomasz12,Coart Elisabeth1,Saad Everardo D.1,Shi Qian3,Sommeijer Dirkje W.456,Bokemeyer Carsten7,Díaz-Rubio Eduardo8,Douillard Jean-Yves9,Falcone Alfredo10,Fuchs Charles S.11,Goldberg Richard M.12,Hecht J. Randolph13,Hoff Paulo M.14,Hurwitz Herbert15,Kabbinavar Fairooz F.13,Koopman Miriam16,Maughan Timothy S.17,Punt Cornelis J. A.18,Saltz Leonard19,Schmoll Hans-Joachim20,Seymour Matthew T.21,Tebbutt Niall C.22,Tournigand Christophe23,Van Cutsem Eric24,de Gramont Aimery2526,Zalcberg John R.27,Buyse Marc228,

Affiliation:

1. International Drug Development Institute, Louvain-la-Neuve, Belgium

2. Hasselt University, Diepenbeek, Belgium

3. Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota

4. The University of Sydney, Camperdown, New South Wales, Australia

5. Academic Medical Centre, Amsterdam, the Netherlands

6. Flevohospital, Almere, the Netherlands

7. Department of Internal Medicine II and Clinic, University of Hamburg, Hamburg, Germany

8. Hospital Clinico San Carlos and Centro de Investigación Biomédica en Red Cáncer, CIBERONC, Madrid, Spain

9. Centre René Gauducheau, St Herblain, France

10. University Hospital S Chiara, Pisa, Italy

11. Dana-Farber Cancer Institute, Boston, Massachusetts

12. West Virginia University Cancer Institute, Morgantown

13. David Geffen School of Medicine, University of California, Los Angeles

14. Instituto de Câncer do Estado de São Paulo, São Paulo, Brazil

15. Genentech, South San Francisco, California

16. Department of Medical Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands

17. Cancer Research UK and the Medical Research Council Oxford Institute for Radiation Oncology, Oxford, United Kingdom

18. Amsterdam University Medical Centrum, Department of Medical Oncology, University of Amsterdam, Amsterdam, the Netherlands

19. Memorial Sloan-Kettering Cancer Center, New York, New York

20. Martin-Luther University, Halle, Germany

21. St James's Hospital, University of Leeds, Leeds, United Kingdom

22. Austin Health, Heidelberg, Victoria, Australia

23. Hôpital Henri Mondor, Creteil, France

24. Division of Digestive Oncology, University Hospitals Gasthuisberg Leuven, Leuven, Belgium

25. Katholieke Universiteit, Leuven, Belgium

26. Franco-British Institute, Levallois-Perret, France

27. School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia

28. International Drug Development Institute Inc, San Francisco, California

Publisher

American Medical Association (AMA)

Subject

General Medicine

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