Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs Tissue Plasminogen Activator Alone in Children with Pleural Empyema

Author:

Livingston Michael H.12,Mahant Sanjay3,Connolly Bairbre4,MacLusky Ian5,Laberge Sophie6,Giglia Lucia1,Yang Connie7,Roberts Ashley7,Shawyer Anna8,Brindle Mary9,Parsons Simon9,Stoian Cristina9,Walton J. Mark1,Thorpe Kevin E.1011,Chen Yang11,Zuo Fei11,Mamdani Muhammad12,Chan Carol3,Loong Desmond1314,Isaranuwatchai Wanrudee101314,Ratjen Felix3,Cohen Eyal3

Affiliation:

1. McMaster Children’s Hospital, McMaster University, Hamilton, Ontario, Canada

2. Golisano Children’s Hospital, University of Rochester Medical Center, Rochester, New York

3. Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

4. Image-Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

5. Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada

6. Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montreal, Quebec, Canada

7. British Columbia’s Children’s Hospital, Division of Respiratory Medicine, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada

8. Health Sciences Centre, Winnipeg, Manitoba, Canada

9. Alberta Children’s Hospital, University of Calgary, Calgary, Alberta, Canada

10. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

11. Applied Health Research Centre, Li Ka Shing Knowledge Institute, St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada

12. Li Ka Shing Centre for Healthcare Analytics Research and Training, St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada

13. Centre for Excellence in Economic Analysis Research (CLEAR), The HUB Health Research Solutions, St Michael’s Hospital, Toronto, Ontario, Canada

14. Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, Ontario, Canada

Publisher

American Medical Association (AMA)

Subject

Pediatrics, Perinatology and Child Health

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