Machine Learning and Statistics in Clinical Research Articles—Moving Past the False Dichotomy

Author:

Finlayson Samuel G.12,Beam Andrew L.3,van Smeden Maarten4

Affiliation:

1. Department of Pediatrics, Seattle Children’s Hospital, Seattle, Washington

2. Department of Genetics, University of Washington, Seattle

3. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

4. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

Abstract

This Viewpoint describes the false dichotomy between statistics and machine learning and suggests considerations in building and evaluating clinical prediction models.

Publisher

American Medical Association (AMA)

Subject

Pediatrics, Perinatology and Child Health

Reference9 articles.

1. [Review of] Bloomfield B ed. The question of artificial intelligence.;McCarthy;Ann Hist Comput,1988

2. Some studies in machine learning using the game of checkers.;Samuel;IBM J Res Develop,1959

3. Statistical modeling: the two cultures (with comments and a rejoinder by the author).;Breiman;SSO Schweiz Monatsschr Zahnheilkd,2001

4. Developing, validating, updating and judging the impact of prognostic models for respiratory diseases.;van Royen;Eur Respir J,2022

5. Calibration: the Achilles heel of predictive analytics.;Van Calster;BMC Med,2019

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