Translation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a Platform Suitable for Development as a Point-of-Care Test
Author:
Affiliation:
1. Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom
2. Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Imperial College London, London, United Kingdom
Publisher
American Medical Association (AMA)
Subject
Pediatrics, Perinatology and Child Health
Link
https://jamanetwork.com/journals/jamapediatrics/articlepdf/2774693/jamapediatrics_pennisi_2021_ld_200048_1616606221.03297.pdf
Reference6 articles.
1. Diagnostic test accuracy of a 2-transcript host RNA signature for discriminating bacterial vs viral infection in febrile children.;Herberg;JAMA,2016
2. Diagnosis of bacterial infection using a 2-transcript host RNA signature in febrile infants 60 days or younger.;Kaforou;JAMA,2017
3. Transcriptomic profiling in childhood H1N1/09 influenza reveals reduced expression of protein synthesis genes.;Herberg;J Infect Dis,2013
4. Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.;DeBerg;PLoS One,2018
5. Simultaneous DNA amplification and detection using a pH-sensing semiconductor system.;Toumazou;Nat Methods,2013
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