Detection of Messenger RNA COVID-19 Vaccines in Human Breast Milk

Author:

Hanna Nazeeh1,Heffes-Doon Ari1,Lin Xinhua2,Manzano De Mejia Claudia2,Botros Bishoy2,Gurzenda Ellen2,Nayak Amrita1

Affiliation:

1. Division of Neonatology, Department of Pediatrics, NYU Langone Hospital–Long Island, NYU Long Island School of Medicine, Mineola, New York

2. Women and Children’s Research Laboratory, NYU Long Island School of Medicine, Mineola, New York

Abstract

This cohort study investigates the presence of COVID-19 vaccine mRNA in the expressed breast milk of lactating individuals who received the vaccination within 6 months after delivery.

Publisher

American Medical Association (AMA)

Subject

Pediatrics, Perinatology and Child Health

Reference6 articles.

1. Exclusion of pregnant and lactating women from COVID-19 vaccine trials: a missed opportunity.;Van Spall;Eur Heart J,2021

2. Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.;Pardi;J Control Release,2015

3. Cutting edge: circulating exosomes with COVID spike protein are induced by BNT162b2 (Pfizer-BioNTech) vaccination prior to development of antibodies: a novel mechanism for immune activation by mRNA vaccines.;Bansal;J Immunol,2021

4. US Food and Drug Administration. Coronavirus (COVID-19) update: FDA authorizes Moderna and Pfizer-BioNTech COVID-19 vaccines for children down to 6 months of age. Released June 17, 2022. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-and-pfizer-biontech-covid-19-vaccines-children

5. Centers for Disease Control and Prevention. COVID-19 vaccines while pregnant or breastfeeding. Accessed March 8, 2021. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html.

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