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Interim Analyses During Group Sequential Clinical Trials

Published:2021-10-19 Issue:15 Volume:326 Page:1524
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Meurer William J.¹²,Tolles Juliana³⁴

Affiliation:

1. Department of Emergency Medicine, University of Michigan, Ann Arbor

2. Department of Neurology, University of Michigan, Ann Arbor

3. Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California

4. Lundquist Institute, Torrance, California

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jama/articlepdf/2784821/jama_meurer_2021_gm_210005_1633987853.2163.pdf

Reference9 articles.

1. Effect of blinatumomab vs chemotherapy on event-free survival among children with high-risk first-relapse B-cell acute lymphoblastic leukemia: a randomized clinical trial.;Locatelli;JAMA,2021

2. Sample size calculation for a hypothesis test.;Stokes;JAMA,2014

3. Group sequential methods in the design and analysis of clinical trials.;Pocock;Biometrika,1977

4. A multiple testing procedure for clinical trials.;O’Brien;Biometrics,1979

5. Discrete sequential boundaries for clinical trials.;Lan;Biometrika,1983

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1. Bayesian Interim Analysis and Efficiency of Phase III Randomized Trials;2024-06-28

2. Focused deterrence: A protocol for a realist multisite randomised controlled trial for evaluating a violence prevention intervention in the UK;PLOS ONE;2024-03-28

3. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials;npj Digital Medicine;2023-11-25

4. Incorporating Efficacy Data from Initial Trials Into Subsequent Evaluations: Application to Vaccines Against Respiratory Syncytial Virus;Epidemiology;2023-11-14

5. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized controlled trials;2023-06-22

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