1. Kadoorie Centre for Critical Care Research and Education, John Radcliffe Hospital, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
2. Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom
3. Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom4Now with Hoffmann-La Roche, Mississauga, Ontario, Canada
4. Kadoorie Centre for Critical Care Research and Education, John Radcliffe Hospital, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom5Royal College of Nursing Research Institute, University of Warwick, Coventry, United Kingdom
5. Oxford Trauma Service, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom
6. Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom
7. Department of Orthopaedic Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom
8. Department of Orthopaedic Surgery, Morriston Hospital, Abertawe Bro Morgannwg University Health Board, Swansea, United Kingdom
9. Kadoorie Centre for Critical Care Research and Education, John Radcliffe Hospital, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom2Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom