What Are Polygenic Scores and Why Are They Important?
Author:
Affiliation:
1. Department of Radiology and Biomedical Imaging, University California, San Francisco
2. Department of Neurology, University California, San Francisco
Publisher
American Medical Association (AMA)
Subject
General Medicine
Link
http:///jama/article-pdf/321/18/1820/17575236/jama_sugrue_2019_it_190005.pdf
Reference6 articles.
1. The personal and clinical utility of polygenic risk scores.;Torkamani;Nat Rev Genet,2018
2. Cardiovascular disease: the rise of the genetic risk score.;Knowles;PLoS Med,2018
3. Screening for prostate cancer: US Preventive Services Task Force recommendation statement.;US Preventive Services Task Force;JAMA,2018
4. Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.;Seibert;BMJ,2018
5. Breast cancer risk from modifiable and nonmodifiable risk factors among white women in the United States.;Maas;JAMA Oncol,2016
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