1. Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Gibbet Hill Campus, Coventry, United Kingdom
2. Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
3. University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom
4. Statistics and Epidemiology Unit, Warwick Medical School, University of Warwick, Gibbet Hill Campus, Coventry, United Kingdom