Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure

Author:

Timsit Jean-Francois1,Azoulay Elie2,Schwebel Carole3,Charles Pierre Emmanuel4,Cornet Muriel5,Souweine Bertrand6,Klouche Kada7,Jaber Samir8,Trouillet Jean-Louis9,Bruneel Fabrice10,Argaud Laurent11,Cousson Joel12,Meziani Ferhat13,Gruson Didier14,Paris Adeline15,Darmon Michael16,Garrouste-Orgeas Maité17,Navellou Jean-Christophe18,Foucrier Arnaud19,Allaouchiche Bernard20,Das Vincent21,Gangneux Jean-Pierre22,Ruckly Stéphane23,Maubon Daniele5,Jullien Vincent24,Wolff Michel1,

Affiliation:

1. UMR1137-IAME Inserm, Paris Diderot University, Paris, France2Medical and Infectious Diseases ICU, Bichat-Claude Bernard University Hospital, Paris, France

2. Saint-Louis University Hospital, Medical ICU, Paris, France

3. Medical ICU, Albert Michallon University Hospital, Grenoble, France

4. Medical ICU, François Mitterrand University Hospital, Dijon, France

5. UMR5525 CNRS-Grenoble Alpes University, Parasitology-Mycology, Grenoble Alpes University Hospital, Grenoble, France

6. Medical ICU, Gabriel Montpied University Hospital, Clermont-Ferrand, France

7. Medical ICU, Lapeyronie University Hospital, Montpellier, France

8. Intensive Care Unit, Department of Anesthesia and Critical Care Medicine, University of Montpellier, Saint Eloi Teaching Hospital, Montpellier, France

9. Medical ICU, Institut de Cardiologie, Hôpital de la Pitié–Salpêtrière, Assistance Publique–Hôpitaux de Paris, Paris, France

10. Medical ICU, André Mignot Hospital, Versailles, France

11. Medical ICU, Edouard Herriot University Hospital, Lyon, France

12. Medical Surgical ICU, CHU de Reims, Reims France

13. Service de Réanimation Médicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France

14. Medical ICU, Bordeaux University Hospital, France

15. Pharmacy Department, Grenoble Alpes University Hospital, Grenoble, France

16. Medical ICU, Saint-Etienne University Hospital, Saint-Priest en Jarez, France

17. Medical-Surgical ICU, Saint-Joseph Hospital Network, Paris, France

18. Reanimation Médicale, CHU Jean Minjoz, Besancon, France

19. Surgical ICU, APHP, Beaujon Hospital, Clichy, France

20. Surgical ICU, Edouard Heriot Hospital, Hospices Civils de Lyon, France

21. Polyvalent ICU, CHI André Grégoire, Montreuil, France

22. Mycology Lab, Rennes University Hospital, Rennes, France

23. ICUREsearch, Department of Biostatistics, Paris, France

24. Pharmacology Department, Georges Pompidou Hospital, Paris Descartes University, Paris, France

Publisher

American Medical Association (AMA)

Subject

General Medicine

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