Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy-Reference-Cited by-同舟云学术

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy

Published:2019-05-28 Issue:20 Volume:321 Page:1993
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Vincent Jean-Louis¹,Francois Bruno²,Zabolotskikh Igor³,Daga Mradul Kumar⁴,Lascarrou Jean-Baptiste⁵,Kirov Mikhail Y.⁶,Pettilä Ville⁷,Wittebole Xavier⁸,Meziani Ferhat⁹,Mercier Emmanuelle¹⁰,Lobo Suzana M.¹¹,Barie Philip S.¹²,Crowther Mark¹³,Esmon Charles T.¹⁴,Fareed Jawed¹⁵,Gando Satoshi¹⁶,Gorelick Kenneth J.¹⁷,Levi Marcel¹⁸,Mira Jean-Paul¹⁹,Opal Steven M.²⁰,Parrillo Joseph²¹²²,Russell James A.²³,Saito Hidehiko²⁴,Tsuruta Kazuhisa²⁵,Sakai Takumi²⁵,Fineberg David²⁶,

Affiliation:

1. Department of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium

2. ICU Department, Inserm CIC-1435 & UMR-1092, CHU Dupuytren, Limoges, France

3. Department of Anesthesiology, Intensive Care and Transfusiology, Kuban State Medical University, Krasnodar, Russia

4. Department of Medicine, Maulana Azad Medical College and associated hospitals, New Delhi, India

5. Centre Hospitalier Universitaire de Nantes, Nantes, France

6. Department of Anesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russia

7. Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

8. Department of Critical Care Medicine, St Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium

9. Faculté de Médecine, Université de Strasbourg (UNISTRA), Hôpitaux Universitaires de Strasbourg, Service de Réanimation, Nouvel Hôpital Civil, Strasbourg, France

10. Médecine Intensive Réanimation, CHRU de Tours, Tours, France

11. Intensive Care Division, Hospital de Base, São José do Rio Preto, SP, Brazil

12. Departments of Surgery and Medicine, Weill Cornell Medicine, New York, New York

13. Department of Medicine, McMaster University and St Joseph’s Hospital, Hamilton, Canada

14. Coagulation Biology Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma

15. Pathology and Pharmacology, Loyola University Medical Center, Maywood, Illinois

16. Acute and Critical Care Center, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan

17. Zymo Consulting Group LLC, Newtown Square, Massachusetts

18. Department of Medicine, University College London Hospitals and Cardiometabolic Programme-NIHR UCLH/UCL BRC, London, United Kingdom

19. Universite´Paris Descartes, Sorbonne Paris Cite´, Faculte´ de Me´-decine Cochin University Hospital, AP-HP, Paris, France

20. Division of Infectious Diseases, Rhode Island Hospital, Providence, Rhode Island

21. Department of Medicine, New Jersey Medical School of Rutgers University, Hackenseck

22. Heart and Vascular Hospital, Hackensack University Medical Center, Hackensack, New Jersey

23. Department of Medicine, Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, Canada

24. National Hospital Organization, Nagoya Medical Center, Nagoya, Japan

25. Asahi-Kasei Pharma Corporation, Tokyo, Japan

26. Asahi-Kasei Pharma America Corporation, Waltham, Massachusetts

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

http:///jama/article-pdf/321/20/1993/17611343/jama_vincent_2019_oi_190044.pdf

Reference13 articles.

1. The epidemiology of sepsis in the United States from 1979 through 2000.;Martin;N Engl J Med,2003

2. Septic shock--evaluating another failed treatment.;Wenzel;N Engl J Med,2012

3. Drotrecogin alfa (activated) in adults with septic shock.;Ranieri;N Engl J Med,2012

4. The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?;Opal;Crit Care Med,2014

5. Sepsis-associated coagulopathy severity predicts hospital mortality.;Lyons;Crit Care Med,2018

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