Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock

Author:

Hernández Glenn1,Ospina-Tascón Gustavo A.2,Damiani Lucas Petri3,Estenssoro Elisa4,Dubin Arnaldo56,Hurtado Javier78,Friedman Gilberto9,Castro Ricardo1,Alegría Leyla1,Teboul Jean-Louis1011,Cecconi Maurizio12,Ferri Giorgio13,Jibaja Manuel14,Pairumani Ronald13,Fernández Paula15,Barahona Diego16,Granda-Luna Vladimir17,Cavalcanti Alexandre Biasi3,Bakker Jan1181920,

Affiliation:

1. Departmento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago

2. Fundación Valle del Lili, Universidad ICESI, Department of Intensive Care Medicine, Cali, Colombia

3. HCor Research Institute–Hospital do Coração, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

4. Hospital Interzonal de Agudos San Martín de La Plata, La Plata, Argentina

5. Sanatorio Otamendi, Buenos Aires, Argentina

6. Cátedra de Farmacología Aplicada, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina

7. Intensive Care Unit, Hospital Español–ASSE, Montevideo, Uruguay

8. Department of Pathophysiology, School of Medicine Universidad de la República, Montevideo, Uruguay

9. Post-Graduation Program in Pneumological Sciences, Department of Internal Medicine, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

10. Service de Réanimation Médicale, Hopital Bicetre, Hopitaux Universitaires Paris–Sud, Paris, France

11. Assistance Publique Hôpitaux de Paris, Université Paris–Sud, Paris, France

12. Humanitas Clinical and Research Center, Department of Biomedical Sciences, Humanitas University, Milan, Italy

13. Unidad de Cuidados Intensivos, Hospital Barros Luco Trudeau, Santiago, Chile

14. Unidad de Cuidados Intensivos, Hospital Eugenio Espejo, Escuela de Medicina, Universidad Internacional del Ecuador, Quito

15. Unidad de Pacientes Críticos, Hospital Guillermo Grant Benavente, Concepción, Chile

16. Unidad de Cuidados Intensivos, Hospital General Docente de Calderón, Universidad Central del Ecuador, Quito

17. Unidad de Cuidados Intensivos, Hospital San Francisco, Pontificia Universidad Católica de Quito, Quito, Ecuador

18. Department of Intensive Care Adults, Erasmus MC University Medical Center, Rotterdam, the Netherlands

19. Department of Pulmonary and Critical Care, New York University, New York, New York

20. Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, New York

Publisher

American Medical Association (AMA)

Subject

General Medicine

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