Oral Cavity Cancer Surgical and Nodal Management

Author:

Eskander Antoine1,Dziegielewski Peter T.2,Patel Mihir R.3,Jethwa Ashok R.4,Pai Prathamesh S.5,Silver Natalie L.6,Sajisevi Mirabelle7,Sanabria Alvaro8,Doweck Ilana9,Khariwala Samir S.4,St. John Maie10

Affiliation:

1. Department of Otolaryngology–Head and Neck Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

2. Department of Otolaryngology, University of Florida College of Medicine, Gainesville

3. Department of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia

4. Department of Otolaryngology–Head and Neck, University of Minnesota Medical School, Minneapolis

5. Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India

6. Head & Neck Institute, Cleveland Clinic, Cleveland, Ohio

7. Department of Otolaryngology, The University of Vermont Medical Center, Burlington

8. Department of Surgery, Universidad de Antioquia, Medellín, Antioquia, Colombia

9. Department of Otolaryngology, Head and Neck Surgery, Carmel Medical Center, Rappaport School of Medicine, Technion, Haifa, Israel

10. Department of Head and Neck Surgery, Ronald Reagan UCLA Medical Center, Los Angeles, California

Abstract

ImportanceLymph node metastases from oral cavity cancers are seen frequently, and there is still inconsistency, and occasional controversies, regarding the surgical management of the neck in patients with oral cancer. This review is intended to offer a surgically focused discussion of the current recommendations regarding management of the neck, focusing on the indications and extent of dissection required in patients with oral cavity squamous cell carcinoma while balancing surgical risk and oncologic outcome.ObservationsThe surgical management of the neck for oral cavity cancer has been robustly studied, as evidenced by substantial existing literature surrounding the topic. Prior published investigations have provided a sound foundation on which data-driven treatment algorithms can generally be recommended.ConclusionsExisting literature suggests that patients with oral cavity cancer should be fully staged preoperatively, and most patients should receive a neck dissection even when clinically N0. Quality standards supported by the literature include separation of each level during specimen handling and lymph node yield of 18 or more nodes. Sentinel lymph node biopsy can be considered in select tumors and within a well-trained multidisciplinary team.

Publisher

American Medical Association (AMA)

Subject

Otorhinolaryngology,Surgery

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. All or Nothing in Surgical Treatment of Precancerous Oral Cavity Lesions;JAMA Otolaryngology–Head & Neck Surgery;2024-09-01

2. The lateral neck in 3 dimensions: A digital model derived from radiology, peer-reviewed literature, and medical illustration;Operative Techniques in Otolaryngology-Head and Neck Surgery;2024-08

3. Sentinel Node Biopsy in Oral Cancer—Indications, Analysis, and Outcomes;JAMA Otolaryngology–Head & Neck Surgery;2024-07-01

4. Sentinel Node Biopsy in Oral Cancer—Indications, Analysis, and Outcomes—Reply;JAMA Otolaryngology–Head & Neck Surgery;2024-07-01

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