1. Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England
2. Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England
3. Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England
4. Statistics and Epidemiology Unit, Warwick Medical School, University of Warwick, Coventry, England
5. Nuneaton, England
6. for the WHIST Trial Collaborators