siRNAs—A New Class of Medicines-Reference-Cited by-同舟云学术

siRNAs—A New Class of Medicines

Published:2023-06-27 Issue:24 Volume:329 Page:2185
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Khvorova Anastasia¹

Affiliation:

1. RNA Therapeutics Institute, UMass Chan Medical School, Worcester, Massachusetts

Abstract

This Genomics and Precision Health article explains how small interfering RNA can modulate disease targets considered “undruggable” by small molecules and biologics.

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jama/articlepdf/2806232/jama_khvorova_2023_it_230007_1687798734.45402.pdf

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4. Inclisiran for the treatment of heterozygous familial hypercholesterolemia.;Raal;N Engl J Med,2020

5. Reversal of siRNA-mediated gene silencing in vivo.;Zlatev;Nat Biotechnol,2018

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