Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke

Author:

Renú Arturo12,Millán Mónica3,San Román Luis4,Blasco Jordi4,Martí-Fàbregas Joan5,Terceño Mikel6,Amaro Sergio127,Serena Joaquín8,Urra Xabier127,Laredo Carlos12,Barranco Roger9,Camps-Renom Pol5,Zarco Federico4,Oleaga Laura4,Cardona Pere10,Castaño Carlos11,Macho Juan4,Cuadrado-Godía Elisa12,Vivas Elio13,López-Rueda Antonio4,Guimaraens Leopoldo13,Ramos-Pachón Anna3,Roquer Jaume12,Muchada Marian14,Tomasello Alejandro15,Dávalos Antonio35,Torres Ferran1617,Chamorro Ángel127,Llull Laura18,Vargas Martha18,Obach Victor18,Rudilosso Salvatore18,Rodríguez-Vázquez Alejandro18,Santana Daniel18,Macías Napoleón18,Serrano Elena18,Moreno Javier18,Pérez de la Ossa Natalia18,Dorado Laura18,Hernández-Pérez Maria18,Gomis Meritxell18,Muñoz Lucia18,Rodríguez-Molinos P.18,Boix Martí18,Palomeras Ernest18,Núñez F.18,Remollo Sebastián18,Werner Mariano18,Vera Victor18,Paul Laura18,Pardo Laura18,Reina Montserrat18,Bashir Saima18,Bojaryn Ursula18,Silva Yolanda18,Guasch Marina18,Murillo Alan18,Rodríguez Álvarez-Cienfuegos Juan18,Comas M.18,Martínez B.18,Nogué E.18,Chirife Oscar18,Quesada Helena18,Lara Blanca18,Paipa Andres18,Aja Lucia18,Mora Paloma18,de Miquel Maria Angel18,Aixut Sónia18,Ferrer Anna Maria18,Marín R.18,Prats-Sánchez Luis18,Delgado-Mederos Raquel18,Martínez-Domeño A18,Branera Joan18,Guerrero R.18,Villalba J,18,Rodríguez A,18,Berga N.18,Jiménez-Xarrié Elena18,Romeral G.18,Ois Ángel18,Jiménez Jordi18,Avellaneda C.18,Cayuela N,18,Rodríguez Ana18,Giralt Eva18,Espona M18,Saldaña J.18,Hernández David18,Ribó Marc18,Piñana Carlos18,Rodríguez Noelia18,Boned Sandra18,Molina Carlos18,Rubiera Marta18,Juega Jesús18,Rodríguez-Luna David18,Pagola Juan18,Garcia-Tonel Alvaro18,Deck Matias18,Sala V18,Sanjuan Estela18,Santana K.18,Losada C.18,Suñe P.18,Jovin Tudor G.18,Leira Enrique18,Rios José18,

Affiliation:

1. Department of Neuroscience, Comprehensive Stroke Center, Hospital Clinic of Barcelona, Barcelona, Spain

2. Institut d’Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain

3. Stroke Unit, Department of Neuroscience, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

4. Neuroradiology Service, Hospital Clinic of Barcelona, Barcelona, Spain

5. Department of Neurology, Stroke Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

6. Neuroradiology Service, Hospital Universitari de Girona Doctor Josep Trueta, Girona, Spain

7. School of Medicine, University of Barcelona, Barcelona, Spain

8. Neurology Service, Stroke Unit, Institut d’Investigació Biomèdica de Girona (IDIBGI), Hospital Universitari de Girona Doctor Josep Trueta, Girona, Spain

9. Department of Interventional Neuroradiology, Bellvitge University Hospital, Hospitalet de Llobregat, Barcelona, Spain

10. Department of Neurology, Bellvitge University Hospital, Barcelona, Spain

11. Interventional Neuroradiology Unit, Department of Neuroscience, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

12. Department of Neurology, Institut Hospital del Mar d’Investigacions Mèdiques, Universitat Autònoma de Barcelona, Barcelona, Spain

13. Department of Neuroradiology, Hospital del Mar, Barcelona, Spain

14. Stroke Unit, Department of Neurology, Hospital Universitari Vall d’Hebron, Barcelona, Spain

15. Department of Neuroradiology, Hospital Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

16. Medical Statistics Core Facility, Clinical Pharmacology Service, IDIBAPS, Hospital Clínic Barcelona, Barcelona, Spain

17. Biostatistics Unit, Faculty of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain

18. for the CHOICE Investigators

Publisher

American Medical Association (AMA)

Subject

General Medicine

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