A Guideline for Reporting Mediation Analyses of Randomized Trials and Observational Studies

Author:

Lee Hopin12,Cashin Aidan G.34,Lamb Sarah E.15,Hopewell Sally1,Vansteelandt Stijn67,VanderWeele Tyler J.8,MacKinnon David P.9,Mansell Gemma10,Collins Gary S.111,Golub Robert M.1213,McAuley James H.414,Localio A. Russell1516,van Amelsvoort Ludo1718,Guallar Eliseo1920,Rijnhart Judith21,Goldsmith Kimberley22,Fairchild Amanda J.23,Lewis Cara C.24,Kamper Steven J.2526,Williams Christopher M.2,Henschke Nicholas27,

Affiliation:

1. Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England

2. School of Medicine and Public Health, University of Newcastle, Callaghan, Australia

3. Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia

4. Neuroscience Research Australia, Sydney

5. College of Medicine and Health, University of Exeter Medical School, Exeter, England

6. Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium

7. Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, England

8. Departments of Epidemiology and Biostatistics, T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts

9. Department of Psychology, Arizona State University, Phoenix

10. College of Health and Life Sciences, Aston University, Birmingham, England

11. NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, England

12. JAMA Editorial Office, Chicago, Illinois

13. Division of General Internal Medicine and Geriatrics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois

14. School of Health Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia

15. Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia

16. Associate Editor, Annals of Internal Medicine

17. Faculty of Health, Medicine, and Life Sciences, Maastricht University, Maastricht, the Netherlands

18. Assoicate Editor, Journal of Clinical Epidemiology

19. Welch Center for Prevention, Epidemiology, and Clinical Research, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland

20. Deputy Editor, Annals of Internal Medicine

21. Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands

22. Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, England

23. Department of Psychology, University of South Carolina, Columbia

24. Kaiser Permanente Washington Health Research Institute, Seattle

25. School of Health Sciences, University of Sydney, Sydney, Australia

26. Nepean Blue Mountains Local Health District, Kingswood, Australia

27. School of Public Health, University of Sydney, Sydney, Australia

Publisher

American Medical Association (AMA)

Subject

General Medicine

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