High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery

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High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery—Reply

Published:2023-01-03 Issue:1 Volume:329 Page:97
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Shi Jia¹,Zhou Chenghui¹,Zheng Zhe¹

Affiliation:

1. National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jama/articlepdf/2800029/jama_shi_2023_lr_220097_1671563411.53029.pdf

Reference6 articles.

1. Effect of high- vs low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery: the OPTIMAL randomized clinical trial.;Shi;JAMA,2022

2. Pharmacokinetics of tranexamic acid during cardiopulmonary bypass.;Dowd;Anesthesiology,2002

3. The dose-response relationship of tranexamic acid.;Horrow;Anesthesiology,1995

4. Population pharmacokinetics of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass.;Grassin-Delyle;Br J Anaesth,2013

5. Exposure-response relationship of tranexamic acid in cardiac surgery.;Zufferey;Anesthesiology,2021

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