Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children

Author:

Ramnarayan Padmanabhan12,Richards-Belle Alvin3,Drikite Laura3,Saull Michelle3,Orzechowska Izabella3,Darnell Robert3,Sadique Zia4,Lester Julie5,Morris Kevin P.67,Tume Lyvonne N.8,Davis Peter J.9,Peters Mark J.1011,Feltbower Richard G.12,Grieve Richard4,Thomas Karen3,Mouncey Paul R.3,Harrison David A.3,Rowan Kathryn M.3,Pathan Nazima13,Daubney Esther13,White Deborah13,Shetty Nayan13,Jones Dawn13,Rad Laura13,O'Malley Laura13,Morris Kevin13,Fox Sarah13,Tooke Carly13,Mohamed Ali Afeda13,Davis Peter13,Marley Helen13,Lean Rebecca13,Dodge Laura13,Aramburo Angela13,Alcantara Laura13,Tos Laura13,Sampaio Helena13,Oruganti Siva13,Bowes Susan13,Hughes Awen13,Peters Mark J13,O'Neill Lauran13,Belfield Holly13,Ray Samiran13,Saxena Rohit13,Vander Johnson Helen13,McHugh Tara13,Jones Gareth13,Armstrong David13,Fraser Laura13,Van Dijke Margrethe13,Piper Ian13,Lillie Jon13,Wellman Paul A13,Williams Aleksandra13,Craen Tabitha13,Perkins Joanne13,Mackerness Christine13,Kashyap Aravind13,Cooper Lindsay13,Lawton Angela13,Verhulst Lynda13,Deep Akash13,Caro Ivan C13,Nsirim Eniola13,Vahid Samira N13,Saikia Bedangshu13,Patel Rekha13,Mason Graham13,Jennings Claire13,Marshall Rebecca13,Pask Danielle13,Sarfatti Avishay13,Oliver Zoe13,Wingfield Katie13,Herrington Sophie13,Silvestre Caterina13,Anderson Laura13,Saxton Maria13,Fazackerley Helen13,Edmonds Naomi13,Thorn Natasha13,Khalid Nosheen13,Khatun Hafiza13,Mayer Anton13,Howlett Alex13,Bryant Jade13,Osman Ahmed13,Cook Amber13,Caruana Lorena13,Thomas Phillipa C13,Prince Nicholas J13,de Queiroz Joana G13,Maccarcari Elena13,Foguet Montserrat R13,Mitting Rebecca13,Darnell Sarah13,Inwald David13,Peters Sam13,Miller Lorna13,Sprinckmoller Stefan13,Koelewyn Abby13,Parslow Roger13,

Affiliation:

1. Section of Anaesthetics, Pain Medicine, and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, United Kingdom

2. Children’s Acute Transport Service, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom

3. Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, United Kingdom

4. Department of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, United Kingdom

5. Parent representative, Sussex, United Kingdom

6. Birmingham Children’s Hospital, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, United Kingdom

7. Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom

8. School of Health & Society, University of Salford, Salford, United Kingdom

9. Paediatric Intensive Care Unit, Bristol Royal Hospital for Children, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom

10. Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Foundation Trust and NIHR Biomedical Research Centre, London, United Kingdom

11. University College London Great Ormond St Institute of Child Health, London, United Kingdom

12. Leeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds, United Kingdom

13. for the FIRST-ABC Step-Down RCT Investigators and the Paediatric Critical Care Society Study Group

Publisher

American Medical Association (AMA)

Subject

General Medicine

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