Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer-Reference-Cited by-同舟云学术

Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer

Published:2020-02-18 Issue:7 Volume:323 Page:646
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Yarmolinsky James¹²,Bull Caroline J.¹²³,Vincent Emma E.¹²³,Robinson Jamie¹²,Walther Axel⁴,Smith George Davey¹²,Lewis Sarah J.¹²,Relton Caroline L.¹²,Martin Richard M.¹²⁵

Affiliation:

1. MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom

2. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

3. School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

4. Bristol Cancer Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom

5. National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jama/articlepdf/2761089/jama_yarmolinsky_2020_oi_200003.pdf

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4. Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer.;Greenaway;Oncotarget,2016

5. Mevalonate pathway antagonist suppresses formation of serous tubal intraepithelial carcinoma and ovarian carcinoma in mouse models.;Kobayashi;Clin Cancer Res,2015

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