Compassionate Use of Tecovirimat for the Treatment of Monkeypox Infection

Author:

Desai Angel N.1,Thompson George R.1,Neumeister Sonja M.1,Arutyunova Anna M.1,Trigg Katelyn1,Cohen Stuart H.1

Affiliation:

1. Division of Infectious Diseases, University of California Davis Medical Center, Sacramento, California

Abstract

This case series describes the clinical resolution of systemic symptoms and lesions, along with any adverse events, in patients with monkeypox infection who were treated with tecovirimat on a compassionate use basis.

Publisher

American Medical Association (AMA)

Subject

General Medicine

Reference6 articles.

1. Clinical features and management of human monkeypox: a retrospective observational study in the UK.;Adler;Lancet Infect Dis,2022

2. Monkeypox virus infection in humans across 16 countries—April-June 2022.;Thornhill;N Engl J Med,2022

3. An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge.;Yang;J Virol,2005

4. Oral tecovirimat for the treatment of smallpox.;Grosenbach;N Engl J Med,2018

5. CDC. 2022 Monkeypox outbreak global map. July 27, 2022. Accessed July 28, 2022. https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html

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