Association of CAG Repeats With Long-term Progression in Huntington Disease

Author:

Langbehn Douglas R.1,Stout Julie C.2,Gregory Sarah3,Mills James A.1,Durr Alexandra4,Leavitt Blair R.5,Roos Raymund A. C.6,Long Jeffrey D.1,Owen Gail3,Johnson Hans J.7,Borowsky Beth8,Craufurd David9,Reilmann Ralf1011,Landwehrmeyer G. Bernhard12,Scahill Rachael I.3,Tabrizi Sarah J.3,

Affiliation:

1. Department of Psychiatry, University of Iowa, Iowa City

2. School of Psychology and Psychiatry, Monash University, Melbourne, Victoria, Australia

3. Huntington’s Disease Centre, UCL Institute of Neurology, University College London, Queen Square, London, United Kingdom

4. Institut du Cerveau et de la Moelle Epinière (ICM), Genetic Department, Assistance Publique–Hôpitaux de Paris, Sorbonne Université, Institut National de la Santé et de la Recherche Médicale Unité 1127, Le Centre National de la Recherche Scientifique, Unités Mixtes de Recherche 7225, Pitié-Salpêtrière University Hospital, Paris, France

5. Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada

6. Department of Neurology, Leiden University Medical Centre, Leiden, the Netherlands

7. Department of Electrical and Computer Engineering, University of Iowa, Iowa City

8. Novartis Pharmaceuticals, East Hanover, New Jersey

9. Manchester Academic Health Sciences Centre, Central Manchester University Hospitals National Health Service Foundation Trust, University of Manchester, Manchester, United Kingdom

10. George-Huntington-Institute, Department of Radiology, University of Münster, Münster, Germany

11. Hertie-Institute for Clinical Brain Research, Department of Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

12. Department of Neurology, Ulm University, Ulm, Germany

Publisher

American Medical Association (AMA)

Subject

Clinical Neurology

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