Mendelian Randomization—A Journey From Obscurity to Center Stage With a Few Potholes Along the Way

Author:

Bandres-Ciga Sara12,Noyce Alastair J.34,Traynor Bryan J.56

Affiliation:

1. Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland

2. Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain

3. Preventive Neurology Unit, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom

4. Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, United Kingdom

5. Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland

6. Department of Neurology, Johns Hopkins University, Baltimore, Maryland

Publisher

American Medical Association (AMA)

Subject

Clinical Neurology

Reference6 articles.

1. Apolipoprotein E isoforms, serum cholesterol, and cancer.;Katan;Lancet,1986

2. How to avoid bias when comparing bone marrow transplantation with chemotherapy.;Gray;Bone Marrow Transplant,1991

3. Mendelian randomization: genetic anchors for causal inference in epidemiological studies.;Davey Smith;Hum Mol Genet,2014

4. Modifiable pathways in Alzheimer’s disease: mendelian randomisation analysis.;Larsson;BMJ,2017

5. Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets.;Zhu;Nat Genet,2016

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