Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease

Author:

Teng Edmond1,Manser Paul T.2,Pickthorn Karen1,Brunstein Flavia3,Blendstrup Mira4,Sanabria Bohorquez Sandra5,Wildsmith Kristin R.67,Toth Bali2,Dolton Michael8,Ramakrishnan Vidya9,Bobbala Ashwini3,Sikkes Sietske A. M.1011,Ward Michael112,Fuji Reina N.13,Kerchner Geoffrey A.14,Farnbach Peter15,Kyndt Chris15,O'Brien Terence15,Yassi Nawaf15,Schwartz Raymond15,Lieten Siddhartha15,Vandenberghe Rik15,Vanhee Frederik15,Bergeron Richard15,Black Sandra15,Cohen Sharon15,Frank Andrew15,Nisker William15,Tartaglia Maria Carmela15,Justesen Annette15,Alexandersen Peter15,Nielsen Soren15,Areovimata Anna15,Anthony Pierre15,Belliard Serge15,Blanc Frédéric15,Ceccaldi Mathieu15,Dubois Bruno15,Krolak-Salmon Pierre15,Mollion Hélène15,Pasquier Florence15,Grimmer Timo15,Kottke-Arbeiter Monika Elisabeth15,Laske Christoph15,Peters Oliver15,Polivka Dörte15,von Arnim Christine15,Bruno Giuseppe15,De Lena Carlo15,Cassetta Emanuele15,Centonze Diego15,Logroscino Giancarlo15,Dautzenberg Paul15,Rutgers Sterre15,Prins Niels15,Czarnecki Maciej15,Dobryniewski Jacek15,Ilkowski Jan15,Klodowska Gabriela15,Krygowska-Wajs Anna15,Kucharski Robert15,Mickielewicz Anatol15,Ratajczak Marcin15,Zboch Marzena15,Zielinski Tomasz15,Abizanda Soler Pedro15,Agüera Morales Eduardo15,Baquero Toledo Miquel15,Blesa González Rafael15,Boada Rovira Mercè15,Del Olmo Rodriguez Antonio15,Krupinski Jerzy15,Linazasoro Cristobal Gurutz15,López Arrieta Jesús15,Riverol Fernandez Mario15,Sanchez Del Valle Diaz Raquel15,Viñuela Fernandez Félix15,Jonsson Michael15,Östlund Henrik15,MacSweeney Josephine Emer15,Mummery Catherine15,Agronin Marc15,Ala Thomas15,Bond Wendy15,Schaerf Frederick15,Brody Mark15,Edwards Keith15,Forchetti Concetta15,Sood Ajay15,Geldmacher David15,Goldstein Mark15,Goodman Ira15,Hart David15,Honig Lawrence15,Justiz William15,Levey Allan15,Losk Scott15,Marshall Gad15,Martinez Walter15,McAllister Peter15,McElveen William Alvin15,Maldonado-Robles Orlando15,Murphy Cynthia15,Nair Malini15,Nair Anil15,Omidvar Omid15,Oskooilar Nader15,Porsteinsson Anton15,Rosenbloom Michael15,Russell David15,Sajjadi Seyed Ahmad15,Pierce Aimee15,Salloway Stephen15,Sha Sharon15,Shah Raj15,Sharma Sanjiv15,Smith William15,Stein Lee15,Stoukides John15,Thein Stephen15,Turner Raymond15,Watson David15,Weisman David15,

Affiliation:

1. Early Clinical Development, Genentech Inc, South San Francisco, California

2. Biostatistics, Genentech Inc, South San Francisco, California

3. Product Development Safety, Genentech Inc, South San Francisco, California

4. Clinical Operations, Genentech Inc, South San Francisco, California

5. Clinical Imaging Group, Genentech Inc, South San Francisco, California

6. Biomarker Development, Genentech Inc, South San Francisco, California

7. Now with Eisai Inc, Woodcliff Lake, New Jersey

8. Roche Products Pty Limited, Sydney, Australia

9. Clinical Pharmacology, Genentech Inc, South San Francisco, California

10. Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands

11. Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands

12. Now with Alector Inc, South San Francisco, California

13. Safety Assessment, Genentech Inc, South San Francisco, California

14. F. Hoffmann-La Roche AG, Basel, Switzerland

15. for the Tauriel Investigators

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

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