Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis

Author:

Witzel Simon12,Maier André3,Steinbach Robert4,Grosskreutz Julian5,Koch Jan C.6,Sarikidi Anastasia7,Petri Susanne7,Günther René89,Wolf Joachim10,Hermann Andreas1112,Prudlo Johannes1213,Cordts Isabell14,Lingor Paul1415,Löscher Wolfgang N.16,Kohl Zacharias17,Hagenacker Tim18,Ruckes Christian19,Koch Birgit3,Spittel Susanne20,Günther Kornelia1,Michels Sebastian1,Dorst Johannes12,Meyer Thomas320,Ludolph Albert C.12,

Affiliation:

1. Department of Neurology, Ulm University, Ulm, Germany

2. German Center for Neurodegenerative Diseases (DZNE), Site Ulm, Ulm, Germany

3. Charité–Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Centre for ALS and other Motor Neuron Diseases, Berlin, Germany

4. Thuringian Neuromuscular Center, Department of Neurology, University Hospital Jena, Jena, Germany

5. Precision Neurology, University of Lübeck, Lübeck, Germany

6. Department of Neurology, University Medical Center Göttingen, Göttingen, Germany

7. Department of Neurology, Hannover Medical School, Hannover, Germany

8. Department of Neurology, Technische Universität Dresden, Dresden, Germany

9. DZNE, Site Dresden, Dresden, Germany

10. Department of Neurology, Diakonissenkrankenhaus, Mannheim, Germany

11. Translational Neurodegeneration Section “Albrecht Kossel,” Department of Neurology, University of Rostock, Rostock, Germany

12. DZNE, Site Rostock/Greifswald, Rostock, Germany

13. Department of Neurology, University Rostock, Rostock, Germany

14. Department of Neurology, Technical University Munich, Munich, Germany

15. DZNE, Site Munich, Munich, Germany

16. Department of Neurology, Medical University Innsbruck, Innsbruck, Austria

17. Department of Neurology, University of Regensburg, Regensburg, Germany

18. Department of Neurology, University Medicine Essen, Essen, Germany

19. University Medical Center of the Johannes Gutenberg-University, Interdisciplinary Center for Clinical Trials (IZKS), Mainz, Germany

20. Ambulanzpartner Soziotechnologie APST GmbH, Berlin, Germany

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

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