Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Author:

Jansen Willemijn J.12,Janssen Olin1,Tijms Betty M.3,Vos Stephanie J. B.1,Ossenkoppele Rik34,Visser Pieter Jelle135,Aarsland Dag67,Alcolea Daniel89,Altomare Daniele1011,von Arnim Christine1213,Baiardi Simone14,Baldeiras Ines151617,Barthel Henryk18,Bateman Randall J.19,Van Berckel Bart20,Binette Alexa Pichet2122,Blennow Kaj23,Boada Merce2425,Boecker Henning26,Bottlaender Michel27,den Braber Anouk28,Brooks David J.293031,Van Buchem Mark A.32,Camus Vincent33,Carill Jose Manuel34,Cerman Jiri35,Chen Kewei2,Chételat Gaël36,Chipi Elena37,Cohen Ann D.38,Daniels Alisha39,Delarue Marion36,Didic Mira4041,Drzezga Alexander2642,Dubois Bruno43,Eckerström Marie44,Ekblad Laura L.45,Engelborghs Sebastiaan4647,Epelbaum Stéphane43,Fagan Anne M.19,Fan Yong48,Fladby Tormod49,Fleisher Adam S.50,Van der Flier Wiesje M.28,Förster Stefan5152,Fortea Juan89,Frederiksen Kristian Steen53,Freund-Levi Yvonne545556,Frings Lars57,Frisoni Giovanni B.58,Fröhlich Lutz59,Gabryelewicz Tomasz60,Gertz Hermann-Josef61,Gill Kiran Dip62,Gkatzima Olymbia63,Gómez-Tortosa Estrella64,Grimmer Timo65,Guedj Eric66,Habeck Christian G.67,Hampel Harald68,Handels Ron1,Hansson Oskar4,Hausner Lucrezia69,Hellwig Sabine70,Heneka Michael T.7172,Herukka Sanna-Kaisa7374,Hildebrandt Helmut75,Hodges John76,Hort Jakub35,Huang Chin-Chang77,Iriondo Ane Juaristi78,Itoh Yoshiaki79,Ivanoiu Adrian80,Jagust William J.8182,Jessen Frank838485,Johannsen Peter86,Johnson Keith A.87,Kandimalla Ramesh62888990,Kapaki Elisabeth N.91,Kern Silke92,Kilander Lena93,Klimkowicz-Mrowiec Aleksandra94,Klunk William E.9596,Koglin Norman97,Kornhuber Johannes98,Kramberger Milica G.99,Kuo Hung-Chou100,Van Laere Koen101102,Landau Susan M.81,Landeau Brigitte36,Lee Dong Young103,de Leon Mony104,Leyton Cristian E.105,Lin Kun-Ju106107,Lleó Alberto89,Löwenmark Malin108,Madsen Karine109,Maier Wolfgang110,Marcusson Jan111,Marquié Marta2425,Martinez-Lage Pablo112,Maserejian Nancy113,Mattsson Niklas4,de Mendonça Alexandre114,Meyer Philipp T.57,Miller Bruce L.115,Minatani Shinobu79,Mintun Mark A.116,Mok Vincent C. T.117118119,Molinuevo Jose Luis120,Morbelli Silvia Daniela121122,Morris John C.19,Mroczko Barbara123124,Na Duk L.125126,Newberg Andrew127,Nobili Flavio128122,Nordberg Agneta67,Olde Rikkert Marcel G. M.129,de Oliveira Catarina Resende15,Olivieri Pauline130131,Orellana Adela2425,Paraskevas George91,Parchi Piero132133,Pardini Matteo134,Parnetti Lucilla37,Peters Oliver135,Poirier Judes136,Popp Julius137138,Prabhakar Sudesh139,Rabinovici Gil D.115,Ramakers Inez H.1,Rami Lorena140,Reiman Eric M.2,Rinne Juha O.141,Rodrigue Karen M.142,Rodríguez-Rodriguez Eloy143,Roe Catherine M.19,Rosa-Neto Pedro136,Rosen Howard J.115,Rot Uros144,Rowe Christopher C.145146,Rüther Eckart147,Ruiz Agustín2425,Sabri Osama18,Sakhardande Jayant148,Sánchez-Juan Pascual149,Sando Sigrid Botne150151,Santana Isabel151617,Sarazin Marie130131,Scheltens Philip28,Schröder Johannes152,Selnes Per49,Seo Sang Won153,Silva Dina114,Skoog Ingmar92,Snyder Peter J.154,Soininen Hilkka155156,Sollberger Marc157158,Sperling Reisa A.159160,Spiru Luisa161162,Stern Yaakov148,Stomrud Erik4,Takeda Akitoshi79,Teichmann Marc43163,Teunissen Charlotte E.28,Thompson Louisa I.164,Tomassen Jori28,Tsolaki Magda165,Vandenberghe Rik166167,Verbeek Marcel M.168,Verhey Frans R. J.1,Villemagne Victor145169,Villeneuve Sylvia2122170,Vogelgsang Jonathan171,Waldemar Gunhild53172,Wallin Anders92,Wallin Åsa K.4,Wiltfang Jens173174,Wolk David A.175,Yen Tzu-Chen107106,Zboch Marzena176,Zetterberg Henrik92177178179180,

Affiliation:

1. Alzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands

2. Banner Alzheimer’s Institute, Phoenix, Arizona

3. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam University Medical Center (UMC), Amsterdam, the Netherlands

4. Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden

5. Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden

6. Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division for Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden

7. Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway

8. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain

9. Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

10. Laboratory Alzheimer’s Neuroimaging and Epidemiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fatebenefratelli, Brescia, Italy

11. Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

12. Division of Geriatrics, University of Goettingen Medical School, Goettingen, Germany

13. Clinic for Neurogeriatrics and Neurological Rehabilitation, University and Rehabilitation Hospital Ulm, Ulm, Germany

14. Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Spain

15. Center for Neuroscience and Cell Biology (CIBB), University of Coimbra, Coimbra, Portugal

16. Neurology Department and Laboratory of Neurochemistry, Centro Hospitalar e Universitário de Coimbra, Praceta Professor Mota Pinto, Coimbra, Portugal

17. Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Coimbra, Portugal

18. Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig, Germany

19. Department of Neurology and the Alzheimer’s Disease Research Center, Washington University School of Medicine in St Louis, St Louis, Missouri

20. Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

21. Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Quebec, Canada

22. Douglas Mental Health University Institute, Montreal, Quebec, Canada

23. Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, Sahlgren’s University Hospital, Mölndal, Sweden

24. Research Center and Memory Clinic of Fundació Alzheimer Centre Educacional, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain

25. CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain

26. Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE), Bonn, Germany

27. Université Paris-Saclay, Service Hospitalier Frédéric Joliot (CEA), French National Centre for Scientific Research (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), BioMaps, Service Hospitalier Frederic Joliot, Orsay, France

28. Department of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

29. Translational and Clinical Research Institute, University of Newcastle upon Tyne, United Kingdom

30. Department of Nuclear Medicine, Positron Emission Tomography Centre, Aarhus University, Aarhus, Denmark

31. Department of Brain Sciences, Imperial College London, London, United Kingdom

32. Department of Neurology, University Hospital Leiden, Leiden, the Netherlands

33. Unite Mixte de Recherche, INSERM U930, French National Centre for Scientific Research (CNRS) ERL, Tours, France

34. Nuclear Medicine Department, University Hospital Marqués de Valdecilla, Molecular Imaging, Instituto de Investigación Sanitaria Valdecilla (IDIVAL), University of Cantabria, Santander, Spain

35. Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

36. Normandie University, University of Caen Normandie (UNICAEN), INSERM, U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Institut Blood and Brain at Caen-Normandie, Cyceron, Caen, France

37. Centro Disturbi della Memoria, Laboratorio di Neurochimica Clinica, Clinica Neurologica, Università di Perugia, Perugia, Italy

38. Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

39. Department of Neurology, Washington University School of Medicine in St Louis, St Louis, Missouri

40. Assistance Publique Hôpitaux de Marseille (AP-HM), Timone, Service de Neurologie et Neuropsychologie, Hôpital Timone Adultes, Marseille, France

41. Aix Marseille Univ, INSERM, Institut de Neurosciences des Systèmes (INS), Marseille, France

42. Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany

43. Department of Neurology, Institut de la Mémoire et de la Maladie d’Alzheimer, Centre de Référence Démences Rares, Hôpital de la Pitié-Salpêtrière, Assistance Publique–Hôpitaux de Paris (AP-HP), Paris, France

44. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden

45. Turku PET Centre, University of Turku, Turku, Finland

46. Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium

47. Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium

48. Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia

49. Department of Neurology, Akershus University Hospital, Lorenskog, Norway

50. Eli Lilly and Company, Indianapolis, Indiana

51. Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

52. Department of Nuclear Medicine, Klinikum Bayreuth, Bayreuth, Germany

53. Danish Dementia Research Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

54. School of Medical Sciences, Örebro University, Örebro, Sweden

55. Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics, Karolinska Institutet Center for Alzheimer Research, Stockholm, Sweden

56. Department of Old Age Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom

57. Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

58. Memory Clinic, University Hospitals and University of Geneva, Geneva, Switzerland

59. Department of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany

60. Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland

61. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Leipzig, Leipzig, Germany

62. Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India

63. Greek Association of Alzheimer’s Disease and Related Disorders, Thessaloniki, Greece

64. Department of Neurology, Fundación Jiménez Díaz, Madrid, Spain

65. Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany

66. Aix Marseille University, AP-HM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, Centre Européen de Recherche en Imagerie Médicale (CERIMED), Nuclear Medicine Department, Marseille, France

67. Department of Neurology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York

68. Sorbonne University, Clinical Research Group no. 21, Alzheimer Precision Medicine, AP-HP, Pitié-Salpêtrière Hospital, Paris, France

69. Universität Heidelberg, Abteilung Gerontopsychiatrie, Zentralinstitut für Seelische Gesundheit Mannheim, Mannheim, Germany

70. Department of Psychiatry and Psychotherapy Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany

71. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital of Bonn, Bonn, Germany

72. Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester

73. Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland

74. Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland

75. Klinikum Bremen-Ost, University of Oldenburg, Institute of Psychology, Oldenburg, Germany

76. Brain and Mind Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

77. Chang Gung Memorial Foundation-Linkou, Taoyuan, Taiwan

78. Center for Research and Advanced Therapies, Centro de Investigación y Ciencias Avanzadas–Alzheimer Foundation, Donostia-San Sebastian, Spain

79. Department of Neurology, Osaka City University Graduate School of Medicine, Osaka, Japan

80. Department of Neurology, Cliniques Universitaires Saint-Luc, Brussels, Belgium

81. Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley

82. Division of Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California

83. Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany

84. Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

85. DZNE, Bonn, Germany

86. Memory Disorder Unit, Copenhagen University Hospital, Copenhagen, Denmark

87. Department of Radiology, Massachusetts General Hospital, Boston

88. Department of Radiation Oncology, Emory University, Atlanta, Georgia

89. Applied Biology, Council of Scientific and Industrial Research (CSIR)-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad, Telangana State, India

90. Department of Biochemistry, Kakatiya Medical College/Mahatma Gandhi Memorial Hospital, Warangal, Telangana State, India

91. National and Kapodistrian University of Athens, School of Medicine, 1st Department of Neurology, Eginition Hospital, Athens, Greece

92. Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

93. Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden

94. Department of Internal Medicine and Gerontology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland

95. Department of Psychiatry, Massachusetts General Hospital, Boston

96. Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania

97. Life Molecular Imaging GmbH, Berlin, Germany

98. Department of Psychiatry and Psychotherapy, University Hospital, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

99. Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia

100. Department of Neurology, Chang Gung Memorial Hospital at Linkou Medical Center, Chang Gung University College of Medicine, Taoyuan, Taiwan

101. Division of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium

102. Department of Imaging and Pathology, Katholieke Universiteit Leuven, Leuven, Belgium

103. Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea

104. Brain Health Imaging Institute, Department of Radiology, Weill Cornell Medicine, New York, New York

105. School of Psychology, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australia

106. Healthy Aging Research Center and Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

107. Department of Nuclear Medicine and Molecular Imaging Center, Linkou Chang Gung Memorial Hospital, Guishan, Taoyuan, Taiwan

108. Memory Clinic, Department of Geriatrics, Uppsala University Hospital, Uppsala, Sweden

109. Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark

110. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany

111. Acute Internal Medicine and Geriatrics, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden

112. Center for Research and Advanced Therapies, CITA-Alzheimer Foundation, Donostia-San Sebastian, Spain

113. Biogen, Cambridge, Massachusetts

114. Faculty of Medicine, University of Lisboa, Lisboa, Portugal

115. Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco

116. Avid Radiopharmaceuticals, Philadelphia, Pennsylvania

117. Division of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China

118. Margaret K.L. Cheung Research Centre for Management of Parkinsonism, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China

119. BrainNow Research Institute, Guangdong Province, Shenzhen, China

120. Alzheimer’s Disease and Other Cognitive Disorders Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Clinic University Hospital, Barcelona, Spain

121. Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy

122. Ospedale Policlinico San Martino, IRCCS, Genoa, Italy

123. Department of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland

124. Department of Biochemical Diagnostics, University Hospital of Białystok, Białystok, Poland

125. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

126. Neuroscience Center, Samsung Medical Center, Seoul, South Korea

127. Myrna Brind Center of Integrative Medicine, Thomas Jefferson University and Hospital, Philadelphia, Pennsylvania

128. Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DINOGMI), University of Genoa, Genoa, Italy

129. Radboudumc Alzheimer Centre, Radboud University Medical Center, Nijmegen, the Netherlands

130. Department of Neurology of Memory and Language, Groupe Hospitalier Universitaire Paris Psychiatry and Neurosciences, Hôpital Sainte Anne, F-75014, Paris, France

131. Université de Paris, Paris, Université Paris-Saclay, BioMaps, CEA, CNRS, INSERM, Orsay, France

132. Istituto delle Scienze Neurologiche di Bologna, IRCCS, Bologna, Italy

133. DIMES, University of Bologna, Bologna, Italy

134. DINOGMI, University of Genoa, Genoa, Italy

135. Klinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin-CBF, Berlin, Deutschland

136. Studies on Prevention of Alzheimer’s Disease (StOP-AD) Centre, Montreal, Quebec, Canada

137. Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich and University of Zürich, Zürich, Switzerland

138. Old Age Psychiatry, Department of Psychiatry, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland

139. Department of Neurology, Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh, India

140. Alzheimer’s Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, IDIBAPS, Barcelona, Spain

141. Turku PET Centre, Turku, Finland

142. Center for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas

143. Neurology Department, Hospital Universitario Marqués de Valdecilla and IDIVAL, Santander, Spain

144. Department of Neurology, Medical Center, Zaloska 7, Ljubljana, Slovenia

145. Department of Molecular Imaging, Austin Health, Melbourne, Victoria, Australia

146. Florey Department of Neuroscience, University of Melbourne, Melbourne, Victoria, Australia

147. Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August University, Göttingen, Germany

148. Cognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia University, New York, New York

149. Service of Neurology, University Hospital Marqués de Valdecilla-IDIVAL, CIBERNED, Santander, Spain

150. Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway

151. Department of Neurology, University Hospital of Trondheim, Trondheim, Norway

152. Section for Geriatric Psychiatry, University of Heidelberg, Heidelberg, Germany

153. Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea

154. Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, The University of Rhode Island, Kingston

155. Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland

156. Neurocenter, Department of Neurology, Kuopio University Hospital, Kuopio, Finland

157. Memory Clinic, University Department of Geriatric Medicine, Felix Platter-Hospital, Basel, Switzerland

158. Department of Neurology, University Hospital Basel, Basel, Switzerland

159. Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts

160. Harvard Aging Brain Study, Department of Neurology, Harvard Medical School, Boston, Massachusetts

161. Geriatrics, Gerontology and Old Age Psychiatry Clinical Department, Carol Davila University of Medicine and Pharmacy-Elias, Emergency Clinical Hospital, Bucharest, Romania

162. Memory Clinic and Longevity Medicine, Ana Aslan International Foundation, Bucharest, Romania

163. Centre de Référence Démences Rares, Pitié-Salpêtrière University Hospital, AP-HP, Paris, France

164. Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island

165. Aristotle University of Thessaloniki, Memory and Dementia Center, 3rd Department of Neurology, George Papanicolau General Hospital of Thessaloniki, Thessaloniki, Greece

166. Laboratory for Cognitive Neurology, Department of Neurosciences, University of Leuven, Leuven, Belgium

167. Neurology Department, University Hospitals Leuven, Leuven, Belgium

168. Departments of Neurology and Laboratory Medicine, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Radboud Alzheimer Centre, Nijmegen, the Netherlands

169. Molecular Biomarkers in Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania

170. McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, Quebec, Canada

171. Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts

172. Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

173. Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany

174. Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany

175. Department of Neurology, University of Pennsylvania, Philadelphia

176. Research-Scientific-Didactic Centre of Dementia-Related Diseases in Scinawa, Medical University of Wroclaw, Wroclaw, Poland

177. Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden

178. Department of Neurodegenerative Disease, University College London (UCL) Queen Square Institute of Neurology, Queen Square, London, United Kingdom

179. UK Dementia Research Institute, London, United Kingdom

180. Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

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