Clinical Evidence of Disease Anticipation in Families Segregating a C9orf72 Repeat Expansion

Author:

Van Mossevelde Sara1,van der Zee Julie2,Gijselinck Ilse2,Sleegers Kristel2,De Bleecker Jan3,Sieben Anne4,Vandenberghe Rik5,Van Langenhove Tim6,Baets Jonathan6,Deryck Olivier7,Santens Patrick3,Ivanoiu Adrian8,Willems Christiana9,Bäumer Veerle2,Van den Broeck Marleen2,Peeters Karin2,Mattheijssens Maria2,De Jonghe Peter6,Cras Patrick10,Martin Jean-Jacques2,Cruts Marc2,De Deyn Peter P.11,Engelborghs Sebastiaan11,Van Broeckhoven Christine2,

Affiliation:

1. Center for Molecular Neurology, VIB, Antwerp, Belgium2Institute Born-Bunge, University of Antwerp, Antwerp, Belgium3Department of Neurology and Memory Clinic, Hospital Network Antwerp Middelheim and Hoge Beuken, Antwerp, Belgium4Department of Neurology, Antwerp University Hospital, Edegem, Belgium

2. Center for Molecular Neurology, VIB, Antwerp, Belgium2Institute Born-Bunge, University of Antwerp, Antwerp, Belgium

3. Department of Neurology, University Hospital Ghent and University of Ghent, Ghent, Belgium

4. Center for Molecular Neurology, VIB, Antwerp, Belgium2Institute Born-Bunge, University of Antwerp, Antwerp, Belgium5Department of Neurology, University Hospital Ghent and University of Ghent, Ghent, Belgium

5. Department of Neurosciences, Faculty of Medicine, KU Leuven, Leuven, Belgium7Department of Neurology, University Hospitals Leuven, Leuven, Belgium

6. Center for Molecular Neurology, VIB, Antwerp, Belgium2Institute Born-Bunge, University of Antwerp, Antwerp, Belgium4Department of Neurology, Antwerp University Hospital, Edegem, Belgium

7. Department of Neurology, General Hospital Sint-Jan Brugge-Oostende, Brugge, Belgium

8. Department of Neurology, Saint-Luc University Hospital and Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium

9. Department of Neurology, Jessa Hospital, Hasselt, Belgium

10. Institute Born-Bunge, University of Antwerp, Antwerp, Belgium4Department of Neurology, Antwerp University Hospital, Edegem, Belgium

11. Institute Born-Bunge, University of Antwerp, Antwerp, Belgium3Department of Neurology and Memory Clinic, Hospital Network Antwerp Middelheim and Hoge Beuken, Antwerp, Belgium

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

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