Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

Author:

Risacher Shannon L.1,McDonald Brenna C.1,Tallman Eileen F.1,West John D.1,Farlow Martin R.2,Unverzagt Fredrick W.3,Gao Sujuan4,Boustani Malaz5,Crane Paul K.6,Petersen Ronald C.7,Jack Clifford R.8,Jagust William J.9,Aisen Paul S.10,Weiner Michael W.11,Saykin Andrew J.1,

Affiliation:

1. Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indiana University Health Neuroscience Center, Indianapolis2Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis

2. Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis3Department of Neurology, Indiana University School of Medicine, Indianapolis

3. Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis4Department of Psychiatry, Indiana University School of Medicine, Indianapolis

4. Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis5Department of Biostatistics, Indiana University School of Medicine, Indianapolis

5. Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis6Indiana University Center for Aging Research, Indianapolis7Regenstrief Institute Inc, Indianapolis, Indiana8Eskenzai Health, Indianapolis, Indiana

6. Department of Internal Medicine, University of Washington, Seattle

7. Department of Neurology, Mayo Clinic, Rochester, Minnesota

8. Department of Radiology, Mayo Clinic, Rochester, Minnesota

9. Department of Neurology, University of California–Berkeley, Berkeley

10. Alzheimer’s Therapeutic Research Institute, University of Southern California, San Diego

11. Departments of Radiology, Medicine, and Psychiatry, University of California–San Francisco, San Francisco15Department of Veterans Affairs Medical Center, San Francisco, California

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

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