Effects of Estrogen Receptor and Human Epidermal Growth Factor Receptor-2 Levels on the Efficacy of Trastuzumab

Author:

Loi Sherene1,Dafni Urania2,Karlis Dimitris3,Polydoropoulou Varvara4,Young Brandon M.5,Willis Scooter5,Long Bradley6,de Azambuja Evandro7,Sotiriou Christos8,Viale Giuseppe9,Rüschoff Josef10,Piccart Martine J.11,Dowsett Mitch12,Michiels Stefan13,Leyland-Jones Brian5

Affiliation:

1. Division of Research and Clinical Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

2. Frontier Science Foundation– Hellas, Athens, Greece3University of Athens, Athens, Greece

3. Frontier Science Foundation– Hellas, Athens, Greece4Athens University of Economics and Business, Athens, Greece

4. Frontier Science Foundation– Hellas, Athens, Greece

5. Avera Cancer Institute, Department of Molecular and Experimental Medicine, Sioux Falls, South Dakota

6. Department of Pathology, University of Chicago, Chicago, Illinois

7. BREAST Datacentre, Institute Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium

8. Breast Cancer Translational Research Laboratory, Institute Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium

9. University of Milan, European Institute of Oncology, Milan, Italy

10. Targos Molecular Pathology GmbH, Kassel, Germany

11. Department of Medicine, Institute Jules Bordet, Universite Libre de Bruxelles and Breast International Group (BIG), Brussels, Belgium12Breast International Group (BIG), Brussels, Belgium

12. Royal Marsden Hospital, London, England

13. INSERM U1018 CESP, Service de Biostatistique et d’Epidémiologie, Villejuif, France

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

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