Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients

Author:

Fehlmann Tobias1,Kahraman Mustafa1,Ludwig Nicole2,Backes Christina1,Galata Valentina1,Keller Verena3,Geffers Lars4,Mercaldo Nathaniel5,Hornung Daniela6,Weis Tanja7,Kayvanpour Elham7,Abu-Halima Masood8,Deuschle Christian910,Schulte Claudia910,Suenkel Ulrike910,von Thaler Anna-Katharina910,Maetzler Walter11,Herr Christian12,Fähndrich Sebastian12,Vogelmeier Claus13,Guimaraes Pedro1,Hecksteden Anne14,Meyer Tim14,Metzger Florian1516,Diener Caroline8,Deutscher Stephanie8,Abdul-Khaliq Hashim17,Stehle Ingo18,Haeusler Sebastian19,Meiser Andreas20,Groesdonk Heinrich V20,Volk Thomas20,Lenhof Hans-Peter21,Katus Hugo7,Balling Rudi4,Meder Benjamin7,Kruger Rejko422,Huwer Hanno23,Bals Robert12,Meese Eckart8,Keller Andreas12124

Affiliation:

1. Chair for Clinical Bioinformatics, Saarland University, Saarbrücken, Germany

2. Junior Research Group of Human Genetics, Saarland University, Homburg, Germany

3. Department of Medicine II, Saarland University Medical Center, Homburg, Germany

4. Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

5. Institute for Technology Assessment, Massachusetts General Hospital, Boston

6. Endometriosis Center, ViDia Clinics, Karlsruhe, Germany

7. Department of Internal Medicine, Heidelberg University, Heidelberg, Germany

8. Institute of Human Genetics, Saarland University, Homburg, Germany

9. Hertie Institute for Clinical Brain Research, Center of Neurology, Department of Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

10. German Center for Neurodegenerative Diseases, Tübingen, Germany

11. Department of Neurology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany

12. Department of Internal Medicine V: Pulmonology, Allergology, Intensive Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany

13. Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marberg, Member of the German Centre for Lung Research (DZL), Marburg, Germany

14. Institute of Sports and Preventive Medicine, Saarland University, Saarbrücken, Germany

15. Department of Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany

16. Center for Geriatric Medicine, University Hospital Tübingen, Tübingen, Germany

17. Department of Pediatric Cardiology, Saarland University, Saarbrücken, Germany

18. Schwerpunktpraxis Hämatologie und Onkologie, Kaiserslautern, Germany

19. Department of Gynecology, University Hospital Würzburg, Würzburg, Germany

20. Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Faculty of Medicine, Saarland University, Homburg, Germany

21. Center for Bioinformatics, Saarland University, Saarbrücken, Germany

22. Parkinson’s Research Clinic, Centre Hospitalier de Luxembourg (CHL), Luxembourg

23. Department of Cardiothoracic Surgery, Völklingen Heart Centre, Völklingen, Germany

24. Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference44 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.;Bray;CA Cancer J Clin,2018

2. Reduced lung-cancer mortality with low-dose computed tomographic screening.;Aberle;N Engl J Med,2011

3. Screening for lung cancer: current status;Hoffmann;Zentralbl Chir,2017

4. Multimodal lung cancer screening using the ITALUNG biomarker panel and low dose computed tomography: results of the ITALUNG biomarker study.;Carozzi;Int J Cancer,2017

5. Exhaled breath analysis for the early detection of lung cancer: recent developments and future prospects.;Nardi-Agmon;Lung Cancer (Auckl),2017

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