Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

Author:

Shen Shuhong1,Chen Xiaojuan2,Cai Jiaoyang1,Yu Jie3,Gao Ju4,Hu Shaoyan5,Zhai Xiaowen6,Liang Changda7,Ju Xiuli8,Jiang Hua9,Jin Runming10,Wu Xuedong11,Wang Ningling12,Tian Xin13,Pan Kaili14,Jiang Hui15,Sun Lirong16,Fang Yongjun17,Li Chi-kong18,Hu Qun19,Yang Minghua20,Zhu Yiping4,Zhang Hui9,Li Chunfu11,Pei Deqing21,Jeha Sima22,Yang Jun J23,Cheng Cheng21,Tang Jingyan1,Zhu Xiaofan2,Pui Ching-Hon22

Affiliation:

1. National Children’s Medical Center, Department of Hematology/Oncology, Key Laboratory of Pediatric Hematology and Oncology of China Ministry of Health, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China

2. State Key Laboratory of Experimental Hematology and Division of Pediatric Blood Diseases Center, Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China

3. Department of Hematology/Oncology, Chongqing Medical University Affiliated Children’s Hospital, Chongqing, China

4. Department of Pediatrics, Key Laboratory of Birth Defects and Related Disease of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China

5. Department of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, China

6. Department of Hematology/Oncology, Children’s Hospital of Fudan University, Shanghai, China

7. Department of Hematology/Oncology, Jiangxi Provincial Children’s Hospital, Nanchang, China

8. Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China

9. Department of Hematology/Oncology, Guangzhou Women and Children’s Medical Center, Guangzhou, China

10. Department of Pediatrics, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

11. Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China

12. Department of Pediatrics, Anhui Medical University Second Affiliated Hospital, Anhui, China

13. Department of Hematology/Oncology, Kunming Children’s Hospital, Kunming, China

14. Department of Hematology/Oncology, Xi’an Northwest Women and Children Hospital, Xi’an, China

15. Department of Hematology/Oncology, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China

16. Department of Pediatrics, Affiliated Hospital of Qingdao University, Qingdao, China

17. Department of Hematology/Oncology, Children’s Hospital of Nanjing Medical University, Nanjing, China

18. Department of Pediatrics, Hong Kong Children’s Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China

19. Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

20. Department of Pediatrics, Xiangya Hospital Central South University, Changsha, China

21. Department of Biostatistics, St Jude Children’s Research Hospital, Memphis, Tennessee

22. Department of Oncology, St Jude Children’s Research Hospital, Memphis, Tennessee

23. Department of Pharmaceutical Sciences, St Jude Children’s Research Hospital, Memphis, Tennessee

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference35 articles.

1. Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL): a prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.;Schlieben;Leukemia,1996

2. Treatment of acute lymphoblastic leukemia.;Pui;N Engl J Med,2006

3. Outcome of treatment in children with Philadelphia chromosome–positive acute lymphoblastic leukemia.;Aricò;N Engl J Med,2000

4. Clinical outcome of children with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia treated between 1995 and 2005.;Aricò;J Clin Oncol,2010

5. Philadelphia chromosome-positive acute lymphoblastic leukemia in China: a retrospective study from the Chinese Childhood Cancer Group.;Gao;Leuk Lymphoma,2016

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