Assessment of Combined Nivolumab and Bevacizumab in Relapsed Ovarian Cancer

Author:

Liu Joyce F.1,Herold Christina2,Gray Kathryn P.3,Penson Richard T.4,Horowitz Neil1,Konstantinopoulos Panagiotis A.1,Castro Cesar M.4,Hill Sarah J.5,Curtis Jennifer1,Luo Weixiu3,Matulonis Ursula A.1,Cannistra Stephen A.6,Dizon Don S.47

Affiliation:

1. Division of Gynecologic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts

2. Division of Breast Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts

3. Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts

4. Department of Medical Oncology, Massachusetts General Hospital, Boston

5. Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts

6. Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts

7. Department of Medical Oncology, Lifespan Cancer Institute, Rhode Island Hospital, Providence

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference34 articles.

1. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.;Zhang;N Engl J Med,2003

2. Prognostic significance of tumor-infiltrating T cells in ovarian cancer: a meta-analysis.;Hwang;Gynecol Oncol,2012

3. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.;Hamanishi;Proc Natl Acad Sci U S A,2007

4. Safety and antitumor activity of anti-PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer.;Hamanishi;J Clin Oncol,2015

5. Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: interim results from the phase 2 KEYNOTE-100 study;Matulonis;Ann Oncol

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