Prevalence of Germline Variants in Prostate Cancer and Implications for Current Genetic Testing Guidelines
Author:
Affiliation:
1. Invitae Corporation, San Francisco, California
2. Tulane University School of Medicine, New Orleans, Louisiana
Publisher
American Medical Association (AMA)
Subject
Oncology,Cancer Research
Link
http:///jamaoncology/article-pdf/5/4/523/17459146/jamaoncology_nicolosi_2019_oi_180119.pdf
Reference20 articles.
1. Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.;Castro;J Clin Oncol,2013
2. Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study.;Bancroft;Eur Urol,2014
3. The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer.;Pomerantz;Cancer,2017
4. Role of genetic testing for inherited prostate cancer risk: Philadelphia prostate cancer consensus conference 2017.;Giri;J Clin Oncol,2018
5. Inherited DNA-repair gene mutations in men with metastatic prostate cancer.;Pritchard;N Engl J Med,2016
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