Blinding, Placebo Effect, and GRADE Methodology—What Is Relevant?

Author:

Bontekoning Nathan12,Groenen Hannah12,Boermeester Marja A.12

Affiliation:

1. Amsterdam UMC location University of Amsterdam, Department of Surgery, Amsterdam, the Netherlands

2. Amsterdam Gastroenterology Endocrinology & Metabolism, Amsterdam, the Netherlands

Publisher

American Medical Association (AMA)

Reference4 articles.

1. The ethical problems with sham surgery in clinical research.;Macklin;N Engl J Med,1999

2. Placebo control and blinding in randomized trials of procedural interventions: a systematic review and meta-regression.;Rajkumar;JAMA Surg

3. RoB 2: a revised tool for assessing risk of bias in randomised trials.;Sterne;BMJ,2019

4. Schünemann? H, Brozek J, Guyatt G, Oxman A. GRADE Handbook. Accessed March 14, 2024. https://gdt.gradepro.org/app/handbook/handbook.html

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