Early Cannabis Use, Polygenic Risk Score for Schizophrenia and Brain Maturation in Adolescence

Author:

French Leon1,Gray Courtney1,Leonard Gabriel2,Perron Michel3,Pike G. Bruce4,Richer Louis5,Séguin Jean R.6,Veillette Suzanne3,Evans C. John7,Artiges Eric8,Banaschewski Tobias9,Bokde Arun W. L.10,Bromberg Uli11,Bruehl Ruediger12,Buchel Christian11,Cattrell Anna13,Conrod Patricia J.14,Flor Herta15,Frouin Vincent16,Gallinat Jurgen11,Garavan Hugh17,Gowland Penny18,Heinz Andreas19,Lemaitre Herve8,Martinot Jean-Luc8,Nees Frauke15,Orfanos Dimitri Papadopoulos16,Pangelinan Melissa Marie1,Poustka Luise9,Rietschel Marcella15,Smolka Michael N.20,Walter Henrik19,Whelan Robert21,Timpson Nic J.22,Schumann Gunter13,Smith George Davey22,Pausova Zdenka23,Paus Tomáš24

Affiliation:

1. Rotman Research Institute, Baycrest, Toronto, Ontario, Canada

2. Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

3. Groupe d’Étude des Conditions de vie et des Besoins de la Population, Cégep de Jonquiere, Jonquiere, Saguenay, Quebec, Canada 4Department of Human Sciences, University of Quebec in Chicoutimi, Chicoutimi, Quebec, Canada

4. Department of Radiology, University of Calgary, Calgary, Alberta, Canada6Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada

5. Department of Health Sciences, University of Quebec in Chicoutimi, Chicoutimi, Quebec, Canada

6. Department of Psychiatry and Centre de Recherche du Centre Hospitalier Universitaire Ste-Justine, University de Montréal, Montreal, Quebec, Canada

7. School of Psychology, Cardiff University, Cardiff, Wales

8. Institut National de la Santé et de la Recherche Medicale (INSERM), Unité Mixte de Recherche (UMR) 1000, Research Unit Imaging and Psychiatry, Commissariat à l’Énergie Atomique (CEA), Direction des Sciences du Vivant, Institut d’Imagerie Biomédicale, Serv

9. Department of Child and Adolescent Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

10. Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neurosciences, Trinity College, Dublin, Ireland

11. Institut für Systemische Neurowissenschaften, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany

12. Physikalisch-Technische Bundesanstalt, Berlin, Germany

13. Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, England20Medical Research Council–Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London

14. Department of Psychiatry and Centre de Recherche du Centre Hospitalier Universitaire Ste-Justine, University de Montréal, Montreal, Quebec, Canada19Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, England

15. Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

16. Neurospin, CEA-Saclay Center, Paris, France

17. Department of Psychiatry, University of Vermont, Burlington24Department of Psychology, University of Vermont, Burlington

18. School of Physics and Astronomy, University of Nottingham, Nottingham, England

19. Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, Berlin, Germany

20. Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany

21. Department of Psychology, University College Dublin, Dublin, Ireland

22. Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, England

23. Department of Physiology and Experimental Medicine, Hospital for Sick Children, University of Toronto, Ontario, Canada31Department of Physiology, University of Toronto, Ontario, Canada32Department of Nutritional Sciences, University of Toronto, Ontario, C

24. Rotman Research Institute, Baycrest, Toronto, Ontario, Canada33Department of Psychology, University of Toronto, Ontario, Canada34Department of Psychiatry, University of Toronto, Ontario, Canada35Child Mind Institute, New York, New York

Publisher

American Medical Association (AMA)

Subject

Psychiatry and Mental health

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