Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression

Author:

Koutsouleris Nikolaos123,Dwyer Dominic B.1,Degenhardt Franziska45,Maj Carlo6,Urquijo-Castro Maria Fernanda1,Sanfelici Rachele17,Popovic David18,Oeztuerk Oemer18,Haas Shalaila S.9,Weiske Johanna1,Ruef Anne1,Kambeitz-Ilankovic Lana10,Antonucci Linda A.11,Neufang Susanne12,Schmidt-Kraepelin Christian12,Ruhrmann Stephan10,Penzel Nora10,Kambeitz Joseph10,Haidl Theresa K.10,Rosen Marlene10,Chisholm Katharine13,Riecher-Rössler Anita14,Egloff Laura14,Schmidt André14,Andreou Christina14,Hietala Jarmo15,Schirmer Timo16,Romer Georg17,Walger Petra18,Franscini Maurizia19,Traber-Walker Nina19,Schimmelmann Benno G.2021,Flückiger Rahel21,Michel Chantal21,Rössler Wulf22,Borisov Oleg6,Krawitz Peter M.6,Heekeren Karsten2223,Buechler Roman2224,Pantelis Christos25,Falkai Peter12,Salokangas Raimo K. R.15,Lencer Rebekka2627,Bertolino Alessandro28,Borgwardt Stefan1427,Noethen Markus4,Brambilla Paolo2930,Wood Stephen J.3132,Upthegrove Rachel13,Schultze-Lutter Frauke1233,Theodoridou Anastasia22,Meisenzahl Eva12,

Affiliation:

1. Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University, Munich, Germany

2. Max-Planck Institute of Psychiatry, Munich, Germany

3. Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom

4. Institute of Human Genetics, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

5. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

6. Institute of Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany

7. Max-Planck School of Cognition, Leipzig, Germany

8. International Max-Planck Research School for Translational Psychiatry, Munich, Germany

9. Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York

10. Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany

11. Department of Education, Psychology, and Communication, University of Bari Aldo Moro, Bari, Italy

12. Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany

13. Institute for Mental Health, University of Birmingham, Birmingham, United Kingdom

14. Department of Psychiatry, Psychiatric University Hospital, University of Basel, Switzerland

15. Department of Psychiatry, University of Turku, Turku, Finland

16. GE Healthcare GmbH (previously GE Global Research GmbH), Munich, Germany

17. Department of Child and Adolescent Psychiatry, University of Münster, Münster, Germany

18. Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, LVR Clinic Düsseldorf, Düsseldorf, Germany

19. Department of Child and Adolescent Psychiatry and Psychotherapy, University of Zürich, Zürich, Switzerland

20. University Hospital of Child and Adolescent Psychiatry, University Hospital Hamburg-Eppendorf, Hamburg, Germany

21. University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland

22. Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Psychiatry Zurich, Zurich, Switzerland

23. Department of Psychiatry and Psychotherapy I, LVR Hospital Cologne, Cologne, Germany

24. Department of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland

25. Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Australia

26. Department of Psychiatry and Psychotherapy, University of Münster, Münster, Germany

27. Department of Psychiatry and Psychotherapy, University of Lübeck, Lübeck, Germany

28. Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy

29. Department of Neurosciences and Mental Health, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

30. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

31. Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia

32. Orygen, the National Centre of Excellence for Youth Mental Health, Melbourne, Australia

33. Department of Psychology and Mental Health, Faculty of Psychology, Airlangga University, Surabaya, Indonesia

Publisher

American Medical Association (AMA)

Subject

Psychiatry and Mental health

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