Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia-Reference-Cited by-同舟云学术

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Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia

Published:2020-07-01 Issue:7 Volume:77 Page:745
ISSN:2168-622X
Container-title:JAMA Psychiatry
language:en
Short-container-title:JAMA Psychiatry

Author:

Kathuria Annie¹²³,Lopez-Lengowski Kara¹²,Jagtap Smita S.¹,McPhie Donna³⁴,Perlis Roy H.¹³,Cohen Bruce M.³⁴,Karmacharya Rakesh¹²³⁴⁵

Affiliation:

1. Center for Genomic Medicine, Massachusetts General Hospital, Boston

2. Chemical Biology Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge

3. Department of Psychiatry, Harvard Medical School, Boston, Massachusetts

4. Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, Massachusetts

5. Program in Neuroscience, Harvard University, Cambridge, Massachusetts

Publisher

American Medical Association (AMA)

Subject

Psychiatry and Mental health

Link

https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2762982/jamapsychiatry_kathuria_2020_oi_200006.pdf

Reference75 articles.

1. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.;Takahashi;Cell,2007

2. Induced pluripotent stem cells: opportunities and challenges.;Okita;Philos Trans R Soc Lond B Biol Sci,2011

3. Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.;Hoffman;Nat Commun,2017

4. Activity-dependent changes in gene expression in schizophrenia human-induced pluripotent stem cell neurons.;Roussos;JAMA Psychiatry,2016

5. Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion.;Lin;BMC Syst Biol,2016

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