Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents

Author:

Lancaster Thomas M.1,Linden David E.2,Tansey Katherine E.3,Banaschewski Tobias4,Bokde Arun L. W.5,Bromberg Uli6,Büchel Christian6,Cattrell Anna7,Conrod Patricia J.8,Flor Herta9,Frouin Vincent10,Gallinat Jürgen11,Garavan Hugh12,Gowland Penny13,Heinz Andreas14,Ittermann Bernd15,Martinot Jean-Luc16,Paillère Martinot Marie-Laure17,Artiges Eric18,Lemaitre Herve16,Nees Frauke19,Orfanos Dimitri Papadopoulos10,Paus Tomáš19,Poustka Luise20,Smolka Michael N.21,Vetter Nora C.21,Jurk Sarah21,Mennigen Eva21,Walter Henrik14,Whelan Robert22,Schumann Gunter7,

Affiliation:

1. Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom2Cardiff University Brain Imaging Research Centre, Cardiff University, Cardiff, United Kingdom

2. Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom2Cardiff University Brain Imaging Research Centre, Cardiff University, Cardiff, United Kingdom3MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff School of Medicine, Cardiff University, Cardiff, United Kingdom

3. MRC Integrative Epidemiology Unit, School of Social and Community Medicine, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom

4. Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

5. Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland

6. University Medical Centre Hamburg-Eppendorf, Hamburg, Germany

7. MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College, London, United Kingdom

8. Department of Psychiatry, Universite de Montreal, CHU Ste Justine Hospital, Montreal, Quebec, Canada10Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College, London, United Kingdom

9. Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

10. Neurospin, Commissariat à l'Energie Atomique, Paris, France

11. Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

12. Departments of Psychiatry and Psychology, University of Vermont, Burlington

13. Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom

14. Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin, Berlin, Germany

15. Physikalisch-Technische Bundesanstalt, Berlin, Germany

16. Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1000, Neuroimaging and Psychiatry Research Unit, University Paris-Sud, Orsay, France19University Paris Descartes, Sorbonne Paris Cité, Paris, France

17. Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1000, Neuroimaging and Psychiatry Research Unit, University Paris-Sud, Orsay, France19University Paris Descartes, Sorbonne Paris Cité, Paris, France20Assistance Publique–Hôpitaux de Paris, Maison de Solenn, Cochin Hospital, Paris, France

18. Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1000, Neuroimaging and Psychiatry Research Unit, University Paris-Sud, Orsay, France21Orsay Hospital, Orsay, France

19. Rotman Research Institute, Baycrest Health Sciences, and Departments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada

20. Department of Child and Adolescent Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

21. Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany

22. Department of Psychology, University College Dublin, Dublin, Ireland

Publisher

American Medical Association (AMA)

Subject

Psychiatry and Mental health

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