Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients
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Published:2022-10-01
Issue:10
Volume:7
Page:1000
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ISSN:2380-6583
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Container-title:JAMA Cardiology
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language:en
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Short-container-title:JAMA Cardiol
Author:
Van Mieghem Nicolas M.1, Deeb G. Michael23, Søndergaard Lars44, Grube Eberhard5, Windecker Stephan6, Gada Hemal78, Mumtaz Mubashir78, Olsen Peter S.44, Heiser John C.910, Merhi William910, Kleiman Neal S.1112, Chetcuti Stanley J.2, Gleason Thomas G.131415, Lee Joon Sup1315, Cheng Wen1617, Makkar Raj R.1617, Crestanello Juan181920, George Barry1820, George Isaac2122, Kodali Susheel2122, Yakubov Steven J.23, Serruys Patrick W.124, Lange Rüdiger25, Piazza Nicolo26, Williams Mathew R.27, Oh Jae K.28, Adams David H.29, Li Shuzhen30, Reardon Michael J.1112, Gitter Christopher31, Meyer Karen31, Roberts Dana31, Bae Richard31, Sorajja Paul31, Sun Benjamin31, Askew Judah31, Eales Frazier31, Flavin Thomas31, Goessl Mario31, Kshettry Vibhu31, Mooney Michael31, Pedersen Wesley31, Poulose Anil31, Roohani Pezhman31, Saeid Farivar Robert31, Shronts Richard31, Tarrel Ronald31, Young Mark31, Butkus Eddy31, Pendleton Kristin31, Fry Robert31, Heine Carl31, La Roe Kristin31, Tran Tin31, Weig Laura31, Agarwal Himanshu31, Langdon Thomas31, Satpathy Ruby31, Batter John31, Bremer Karen31, Indukuri Unajyothi31, Baas Marijke31, Oomes-Sistermans Corry31, Smits Manola31, Coenen Carien31, Driesen Inge31, Lauryssen Lia31, Poorter Margreet31, Schaap Jeroen31, Bentala Mohamed31, den Heijer Peter31, Pieter Jan31, Remmers Michel31, Story Marie31, van Erven Paul M.M.31, Verbiest Henk31, Vos Jeroen31, Bennett Michelle31, Dunaj Wendy31, Seaton Deborah31, Waller Deborah31, Khandheria Bijoy31, Bajwa Tanvir31, O'Hair Daniel31, Ahmed Arshad31, Allaqaband Suhail31, Gheith Ayman31, Marriott Elizabeth31, Qhavi Ajaz31, Saxena Varun Kumar31, Shhadeh Akram31, Werner Paul31, Yeomans Christine31, Bessette Lynn31, Byrne Jessica31, Kieckhefer Heather31, Munoz Marleny31, Russo Elizabeth31, Klein Jason31, Morgan Michael31, Byrne Timothy31, Caskey Michael31, Amabile Orazio31, Brady Kevin31, Chung Steven31, Dacanay Kelly31, Fang H. Kenith31, Franz Douglas31, Kelly Claire31, Loli Akil31, Payne Jeremy31, Pershad Ashish31, Wang Norman31, Lott Jessi31, Pool-Owens C. Angele31, Porter Charlotte31, Hennan Jeffrey A.31, Garrett H. Edward31, Paulus Basil31, Craig John31, Elijovich Lucas31, Samaha Joseph31, Wolf Bradley31, Wright Lance31, Zoghbi Gilbert31, Willcott Leslie31, Roberts Brad31, Hebeler Robert31, Stoler Robert31, Graybeal Dion31, Grayburn Paul31, Henry Carl31, Mir Osman31, Vallabhan Ravi31, Fanous Matthew31, Kaufman Jenifer31, Chang James31, Manning Warren31, Riley Marilyn31, Khabbaz Kamal31, Laham Roger31, Popma Jeffrey31, Burke David31, Caplan Louis31, Chui Shing Fung31, Guibone Kim31, Kumar Sandeep31, Lioutas Vasileios-Arsenios31, Liu David31, Nathan Senthil31, Pinto Duane31, Searls D. Eric31, Fisher Susan31, Guirgues Lindsay31, Henderson Sue31, Loving Laura Ashley31, McWalters Nicole31, Patterson Kelly31, Burkart Jesse31, Carcedo Bryan31, Stacey Russell31, Bladergroen Mark31, Lim David Scott31, Edmonson Supakunya31, Epps Stacey31, Katz Marc Robert31, Ng Ken31, Sangha Amandeep31, Aucoin Jennifer31, Roberts Monique31, Aubin Jaime31, Hotard Callie31, Tassin Michelle31, Fail Peter31, Feinberg Edgar31, Netherland Donald31, Abben Richard31, Allam Mohamad31, Bates Michael31, Dearman Richard31, Gervais Donald31, Haight Edward31, Metes Michael31, Naquin Jeanette31, Tedesco Victor31, Thibodeaux Lisa31, Thompson Karen31, Aberle Sally31, Amaro Dana31, Grey William31, Rose Geoffrey31, Scherer Markus31, Rinaldi Michael31, Skipper Eric31, Bridges Charles31, Downey William31, Iyengar Phaniraj31, Martin Jerry31, Ryan Liam31, Stiegel Robert31, Story John S.31, Alsabaawi Khaled31, Gheorghiu Mitch31, Singh Chetana31, Yashar Jason31, Siegel Robert31, Cheng Wen31, Makkar Raj31, Altman Karen31, Jilaihawi Hasan31, Kar Saibal31, Khouw Stephanie31, Mody Cyrus31, Ramzy Danny31, Salseth Tracey31, Stegic Jasminka31, Trento Alfredo31, Lazarte Rosa31, Sohn Jeanie31, Hahn Rebecca31, Khalique Omar31, George Isaac31, Kodali Susheel31, Williams Mathew31, Gonzalez Castellon Marco31, Gutierrez Contreras Jose31, Kitago Tomoko31, Kummer Benjamin31, Lekic Tim31, Miller Eliza31, Naka Yoshifumi31, Nazif Tamim31, Qureshi Abid31, Rostanski Sara31, Smith Craig31, Willey Joshua31, Yaghi Shadi31, Abreu Leana31, Clement Emerson31, Sabir Sajjad31, Aji Janah31, Bowen Frank31, Kaddissi Georges31, Mirsen Thomas31, Muntazar Muhammad31, Ogbara Jeffrey31, Rosenbloom Michael31, Schell Wendy31, Then Ryna31, Carl Heidi31, Huang Hong31, Kreydi Ghassan31, Wolak Heather31, Sandidge Gregory31, Ali Omar31, Asfaw Zewditu31, Henry Scott31, Kafi Ali31, Schreiber Theodore31, Andaya Lourdes31, Baciewicz Frank31, Bassett Joseph31, Choksi Nishit31, Kassas Safwan31, Munir Ahmad31, Kothmeier Franziska31, Stroh Annemarie31, Goppel Gertrud31, Hettich Ina31, Bleiziffer Sabine31, Hengstenberg Christian31, Opitz Anke31, Ruge Hendrik31, Badiu Catalin Constantin31, Brenner Susanne31, Ehlmidi Yacine31, Herold Ulf31, Kasel Albert31, Kreuzpointner Robert Josef31, Lange Rüdiger31, Mazzitelli Domenico31, Poppert Holger31, Seifert Christian31, Vincze Dóra31, Voss Bernhard31, Camuglia Krista31, Cowhig Dahlia31, Newbold Stephanie31, Pierce Cynthia31, Wootton Samantha31, Vemulapalli Sreekanth31, Velazquez Eric31, Harrison J. Kevin31, Hughes G. Chad31, Ali Yasmin31, Babi Ali31, Banks Adam31, Gaca Jeffrey31, Glower Donald31, Gokhale Sankalp31, Halim Sharif31, Hendry Robert31, Hernandez Christian31, Kiefer Todd31, Klein Michael31, Kolls Bradley31, Marrotte Eric31, Pineda Maldonado Andres31, Price Andrew31, Sherwood Matthew31, Swisher Christa31, Van Wyck David31, Vavalle John31, Vora Amit31, Wang Andrew31, Zeylikman Yuriy31, Amber Kara31, Barnitt Anne31, Lamm Janet31, Mandelstam Lara31, Schroeder Ryan31, Sumner Roxanne31, Nair Deepu31, De Ajanta31, Gaudiani Vincent31, Joye James31, Brown Lidia31, Hessler Christine31, Rammohan Chad31, Vial Conrad31, Charles Elizabeth31, DeQuesada Angela31, Kaner Maria31, Mathewson Sonya31, Pitts Kristy31, Wheeler Lauren31, Wilson Ashley31, Davidson Estella31, Frohwein Stephen31, Lerakis Stamatios31, Merlino John31, Sullivan Angela31, Babaliaros Vasilis31, Guyton Robert31, Thourani Vinod31, Anderson Aaron31, Belagaje Samir31, Benameur Karima31, Devireddy Chandan31, Greene James31, Harrison Amy31, Hudson Kristen31, Leshnower Bradley31, Lieppe William31, Macheers Steven31, Mavromatis Kreton31, Miller Jeffrey31, Nahab Fadi31, Sanders Keith A.31, Sarin Eric31, Stewart James31, Winkel Daniel31, Duininck Liesbeth W.31, Gussinklo Titia31, Jadoenath-Oedai Shashikala31, Ruiter Arno31, van den Berg Nico31, van der Velden-Macauley Liz E.N.31, van Huis Maaike31, Verelst Silvia G.R.31, Geleijnse Marcel Leonard31, Vletter Wim B.31, Bekker Margaretha31, Kappetein A. Pieter31, Van Mieghem Nicolas M.31, Bekkers Joseph A.31, Biesheuvel Karla31, Birim Ozcan31, Bol Raap Goris31, Daemen Joost31, de Jaegere Peter Paul31, de Lind van Wijngaarden Rob31, Khajeh Ladbon31, Kik Charles31, Koudstaal Peter J.31, Oei Frans B.S.31, Scheele Maaike31, van de Woestijne Pieter31, van Geuns Robert-Jan31, van Leeuwen Wouter J.31, Henderson Amy31, Straight Faye31, Schneider David31, Tischler Marc31, Dauerman Harold31, Ittleman Frank31, Schmoker Joseph31, Abernethy Abraham31, Alkhalil Imran31, Azarbal Amir31, Chava Sreedivya31, Commichau Christopher31, Coyle David31, Denkmann Jan31, Destephan Christine31, Ehle Gregory31, El-Haddad Mohamed31, Falduto Catherine31, Gorman Mark31, Kadavath Sabeeda31, Leavitt Bruce31, Mack Allison31, Malasana Gangadhar31, Moossavi Shahab31, Phuong Newton31, Rambod Mehdi31, Seecheran Naveen31, Sharma Ashwini31, Terrien Edward31, Worgan Barbara31, Zeglin-Sawczuk Magdalena31, Burgess Brian31, Killbride Susan31, Temple Amy31, Burnside Joyce31, Good Christopher31, Agarwal Shikhar31, Casale Alfred31, Skelding Kimberly31, Carter Russell31, Cummings Christopher31, Grana Vicente31, Haegerl Carl31, Harjai Kishore31, Holland Neil31, Singh Deepak31, Stahl Russell31, Stella Joseph31, Stewart Birute31, Long Doug31, Wood Kim31, Alexander Donna31, Barton Sally31, Logtens Elaine31, Marsh Anna-Marie31, McAdam John31, Kovac Jan31, Mariscalco Giovanni31, Spyt Tomasz31, Garimella Soumitra31, Szostek Jacek31, Zlocha Viktor31, Kirkland Lavonda31, Reid Lori31, Reilly Susan31, Menderhall Melody31, Martin William31, Park Steven31, Seshiah Puvi31, Smith J. Michael31, Gersch Karen31, Hiratzka Loren31, Kachoris John31, Okum Eric31, Cardozo Maria31, Cyr Giselle31, Duvall W. Lane31, Flynn Aidan31, Krupowies Nancy31, Parker Matthew31, Hagberg Robert31, McKay Raymond31, Azemi Talhat31, Brown Robert31, Fusco Daniel31, Hammond Jonathan31, Hosley Catherine31, Kiernan Francis31, Margey Ronan31, Preissler Paul31, Sadiq Immad31, Silverman Isaac31, Taboada Susan31, Underhill David31, Escobar Jose31, Lopez Becky31, Mullin Stephanie31, Quesada Christine31, Lawrence Tracy31, Naqvi Tasneem31, Matthews Ray V.31, Starnes Vaughn31, Clavijo Leonardo31, Cunningham Mark31, Kim-Tenser May31, Sanossian Nerses31, Shavelle David31, DelMotte Danielle31, Henry Samantha31, Moltrassie JoAnne31, Solanki Ashish31, Cooper Raymond31, Lee James31, Parikh Sachin31, Wang Dee Dee31, Zweig Brian31, O'Neill William31, Paone Gaetano31, Borgi Jamil31, Brewer Robert31, Eng Marvin31, Greenbaum Adam31, Guerrero Mayra31, Miller Daniel31, Mitsias Panayiotis31, Morgan Jeffrey31, Nemeh Hassan31, Alcaide Muñoz Javier31, Medina Fernandez Maria31, Carrasco Chinchilla Fernando31, Rodríguez Bailón Isabel31, Hernández García José Maria31, Such Miguel31, Alonso-Briales Juan31, De La Cruz Cosme Carlos31, Dominguez-Franco Antonio31, Mataró López Maria J.31, Melero Jose Maria31, Muñoz-Garcia Antonio-Jesus31, Sanchez Espin Gemma31, Fernández Maese Jose Manuel31, Torres Marta31, Villa Suarez Esther31, De La Hera Jesus M.31, Llosa Cortina Juan Carlos31, Morís de la Tassa Cesar31, Avanzas Fernández Pablo31, Benavente Fernández Lorena31, Calleja Sergio31, Del Valle Raquel31, Morales Pérez Carlos31, Silva Jacobo31, Bluntschli Eva31, Keller Dorothee31, Maritz Sandra31, Ruest Rafael31, Schönenberger Christa31, Trovato Moreno31, Brugger Nicolas31, Göber Volkhard31, Kurmann Reto31, Reineke Sylvia31, Zürcher Fabian31, Carrel Thierry31, Windecker Stephan31, Arnold Marcel31, Balasubramaniam Rupashani31, Bellwald Sebastian31, Beyeler Morin31, Broeg Anne31, Bühlmann Monika31, Büllesfeld Lutz31, Capek Lukas31, Chaloulos-Lakovidis Panagiotis31, Corpataux Noe31, Englberger Lars31, Gloekler Steffen31, Goldlin Martina Beatrice31, Huber Christoph31, Khattab Ahmed31, Kurmann Rebekka31, Lanz Jonas31, Liesirova Kai31, Maamari Basel31, Mattle Heinrich31, Meinel Thomas31, Panos Leonidas31, Praz Fabien31, Schönhoff Florian31, Sleszak Agnieszka31, Spirito Alessandro31, Stortecky Stefan31, Vaisnora Lukas31, Von Martial Rascha31, Wenaweser Peter31, Zuk Katarzyna31, Musso Iris31, Allen Meredith31, Gonzales Michael31, Horton Ken31, Doty John31, Whisenant Brian31, Caine William31, Clayson Stephen31, Harkness James31, Hoesch Robert31, Huan Mengjing Chloe31, Jones Kent31, Miner Edward31, Reid Bruce31, Sunderman Elizabeth31, Citro Kathleen31, Fisher Michele31, Willhide Judi31, Corretti Mary31, Conte John31, Mandal Kaushik31, Resar Jon31, Chacko Matthews31, Hasan Rani31, Heil Barbara31, Marsh Elizabeth31, Price Joel31, Sciortino Chris31, Shah Ashish31, Tolentino Jennie31, Bui Anh31, Lee Ming Sum31, Watanabe Colin31, Aharonian Vicken31, Moore Naing31, Pfeffer Thomas31, Ajani Zahra31, Mansukhani Prakash31, Sangha Navdeep31, Yun Kwok31, Hylander Susanne31, Bäck Magnus31, Corbascio Matthias31, Hillebrant Carl-Gustaf31, Rück Andreas31, De Palma Rodney31, Feldt Kari31, Kostulas Konstantinos31, Settergren Magnus31, Yamasaki Keita31, Anderson Michelle31, Bloomfield Charlotte E.31, Burtonwood Natalie31, Harland Charlotte31, Somers Kathryn31, Ware Tracey L.31, Deakin Sarah31, Geldard Susan31, Schlosshan Dominik31, Blackman Daniel31, Kaul Pankaj31, Evans Betsy31, Javangula Kalyana C.31, Limaye Sameer S.31, Malkin Christopher J.31, Wanklyn Peter31, Farhi Anita31, Manapat Arika31, Maranan Leandro31, Mihelis Effe31, Ng Amelia31, Ricketts Melissa31, Kronzon Itzhak31, Perk Gila31, Brinster Derek31, Kliger Chad31, Azhar Salman31, Bonomo Roger31, Dharva Rubin31, Fontana Gregory31, Mandel Steven31, Mehla Priti31, Patel Nirav31, Plestis Konstadinos31, Fox Stephanie31, Mardell Stephen31, Novick Teresa31, Sandie Kelsey31, de Jonge Wes31, McLeod Claudia31, Mroz Luke31, Weigand Andrea31, Chu Michael31, Kiaii Bob31, Teefy Patrick31, Bagur Rodrigo31, Debicki Derek31, Diamantouros Pantelis31, Gofton Teneille31, Mandzia Jennifer31, McKenzie F. Neil31, Mirsattari Seyed31, Valdis Matthew31, Young Bryan31, Klein Wendy31, Sawicki Kristina31, Dajani Khaled31, Darki Amir31, Bakhos Mamdouh31, Leya Ferdinand31, Biller Jose31, Lewis Bruce31, Morales-Vidal Sarkis31, Schneck Michael31, Schwartz Jeffrey31, Tuchek J. Michael31, Biddle Amanda31, Ernst Dereen31, Haubenschild Julie31, Howe-Clayton Desirae31, Johnson Ramona31, Mundt Pamela31, Reiter Jacqulyn31, Bruce Charles31, Freeman William31, Kutzke Kim31, Maalouf Joseph31, Nkomo Vuyisile31, Pislaru Sorin31, Sinak Lawrence31, Pochettino Alberto31, Sandhu Gurpreet31, Alkhouli Mohamad31, Best Patricia31, Bresnahan John31, Eleid Mackram31, Fulgham Jimmy31, Greason Kevin31, Gulati Rajiv31, Holmes David31, Maor Elad31, Mathew Verghese31, Meissner Irene31, Panaich Sidakpal31, Peterson Angela31, Radford Jonathan31, Raphael Claire31, Reeder Guy31, Sanon Saurabh31, Sarraf Mohammad31, Scharf Eugene31, Suri Rakesh31, Swenson Courtney31, Williams Lindsy31, Jiang Zuyi31, Lapierre Serge31, Phan Thi Mong Ngoc31, Buithieu Jean31, de Varennes Benoit31, Piazza Nicolo31, Lachapelle Kevin31, Liam Durcan31, Martucci Giuseppe31, Blömer Han J.31, Herder Wiebren31, Van der Geest Els31, van der Wal Metske31, Izaksson Rob31, Kootstra Hetty31, Pultrum Maarten31, Walinga Tamara31, Boonstra Piet W.31, van Boven Adrianus Johannes31, Amrane Hafid31, Hofma Sjoerd31, Schuiling Wouter J.31, Terluin Hanny31, Timmerman Margje31, van der Weerdt Arno Peter31, van Rooij Frank31, Vossenberg Tessel N.E.31, Barnes Caroline31, Griffin Sandra31, Goldstein Steven31, Marcus Rachel31, Wang Zuyue31, Widell Jared31, Bafi Ammar31, Waksman Ron31, Choi Joseph31, Corso Paul31, Laureno Robert31, Lin Mark31, Lowery Robert31, Malla Prerna31, Pichard Augusto31, Satler Lowell31, Shults Christian31, Decklever Cecily31, Evans Danika31, Tuttle Kendra31, Klein Marc31, Marcus Richard31, Chawla Atul31, Hockmuth David31, Jacoby Michael31, Jenson Bart31, McAllister David31, Prabhakar Ganga31, Verhofste Marnix31, Morin Colette31, Potvin Lucie31, St. Jean Nathalie31, Garceau Patrick31, Asgar Anita31, Cartier Raymond31, Bonan Raoul31, Dominquez Manuel31, Dorval Jean-Francois31, Ibrahim Reda31, Lavoie Marc-Andre31, Benner Autumn31, Brunetti Deborah31, Ciprich Christine31, Lobur Elena31, Lonergan Noele31, McGlew Suellyn31, Oplinger Jeanne31, Oster Tracy31, Polise Lucille31, Purpura Jenelle31, Sentman Susan31, Van Zile Catherine31, Arogundade Olasunkanmi31, Gillan Linda31, Koulogiannis Konstantinos31, Brown John31, Kipperman Robert31, Blitz Lawrence31, Cohen Barry31, English Karen31, Genereux Philippe31, Magovern Christopher31, Rosenberg Richard31, Safirstein Jordan31, Slater James31, Turner Joanne31, Xydas Steve31, Jones Teresa31, Montgomery Susan31, Barry Michael31, Kovach Todd31, Navas Jorge31, Patel Vijay31, Lin Lang31, Rovin Joshua31, Arora Ajay K.31, Ofenloch John31, Schneider Jean-Raphael31, Spriggs Douglas31, Stone Lisa31, Turner Nancy31, Basnet Sandeep31, Bhat Arjun31, Fusilero Michael31, Muthiki Sowmya31, Muthyala Samatha31, Saint Vrestil Nicole31, Sharma Madhav31, Singh Julie31, Chaudhry Farooq31, Sengupta Partho31, Adams David31, Sharma Samin31, Tang Gilbert31, Anyanwu Anelechi31, Bronster David31, Dangas George31, Kini Annapoorna31, Stelzer Paul31, Stewart Allan31, Swain Julie31, Annunziato Samantha31, Chan Grace31, Delliliune Diane31, Garzon Ruby31, Seeratan Vidya31, Rosman David31, Suma Valentin31, Trost Biana31, Hartman Alan31, Katz Stanley31, Rutkin Bruce31, Boutis Loukas31, Carey Ruthanne31, DeAngelis Teresa31, DeOrchis Vincent31, Esposito Rick31, Han Michael31, Jauhar Rajiv31, Kaplan Barry31, Laighold Saaron31, Meraj Perwaiz31, Palazzo Robert31, Parihar Raminder31, Podwall David31, Wright Paul31, Yu Pey-Jen31, Abu Miriam31, Bavbekova Saniye31, Bowden Morgan31, Clark Emily31, Gaudio Stephanie31, Houanche Pascale31, Kalish Chloe31, Kapitman Anna31, Lee Hanah31, Morales Vanessa31, Oviedo Franklin31, Pushkar Illya31, Robin Tonya31, Shaheen Devin31, Sin Danielle31, Taylor Zachary31, Tovar Joseph31, Van Daele Jessie31, Vidal Samantha31, Yung Lau Yan31, Saric Muhamed31, Galloway Aubrey31, Jilaihawi Hasanian31, Attubato Michael31, Fara Michael31, Grossi Eugene31, Ischida Koto31, Loulmet Didier31, Siller Keith31, Staniloae Cezar31, Torres Jose31, Zhang Cen31, Hartlev Christie31, Huffman Andrew31, Jones Danielle31, Kellum Annie31, Liptrot Roderick31, Orsinelli David31, Ryan James Michael31, Ryan Thomas31, Crestanello Juan31, George Barry31, Lilly Scott31, Rushing Gregory31, Grose Noah31, Kilic Ahmet31, Lee Vivien31, Mazzaferri Ernest31, Mutgi Smil31, O'Neil Susan31, Perchuk Alex31, Sai-Sudhakar Chittoor31, Slivka Andrew31, Cheatham John P.31, Hanes Stacie31, Banowetz Michael31, Dautenhahn David31, Mehl Brad31, Bodenhamer Robert Mark31, Ghani Mohammad31, Raikar Goya31, Randolph John31, Tahirkheli Naeem31, Wasemiller Wayne31, Williams John31, Amoroso Elisa31, Holt Shelley31, Tucker Claire31, Martin Randolph31, Kauten James31, Rajagopal Vivek31, Awad Eric31, Brown W. Morris31, Dean David31, Gott John31, Karmpaliotis Dimitrios31, Meduri Christopher31, Polsani Venkateshwar31, Rinehart Sarah31, Russell Christopher31, Seiden Lawrence31, Serbanescu Andrei31, Vannan Mani31, Butler Kim31, Elsessor Kayla31, Fehr Brittany31, Hancock Anthony31, Hollister Regina31, MacFarlane Dawn31, Rodgers Courtney31, Todd Anita31, Eubanks Veronica31, Spangler Jessica31, Wirt Katie31, Wonders Brook31, Bachinsky William31, Gada Hemal31, Maini Brijeshwar31, Mumtaz Mubashir31, Aneja Parul31, Loran David31, Shah Jagdish31, Gebhardt Linda31, Jones Ursula31, Lauterborn Marjo31, John Henriette31, Parthier Sonja31, Schaprian Katja31, Twelker Kaja31, Nickenig Georg31, Welz Armin31, Bode Felix J.31, Fuchs Angela31, Grube Eberhard31, Mellert Friedrich31, Petzold Gabor31, Sedaghat Alex31, Sinning Jan-Malte31, Vasa-Nicotera Mariuca31, Werner Nikos31, Bang Helle31, Brodersen Bente Birgitte31, Christensen Pernille Roed31, Eriksen Elsebet31, Groth Susanne31, Jensen Larsen Mie Christa31, Johansen Mette Ellegaard31, Kristensen Line31, Lilleør Thomas Nikolaj31, Lund Larsen Lisette31, Preis Anne-Cathrine31, Rieck-Broberg Jeanette31, Rosenberg Tine31, Ihlemann Nikolaj31, Møller Jacob31, Noerager Betina31, Olsen Peter Skov31, Søndergaard Lars31, Steinbrüchel Daniël31, Andersen Henrik31, Arendrup Henrik31, Bieliauskas Gintautas31, Carranza Christian31, De Backer Ole31, Franzen Olaf31, Hansen Klaus31, Højgaard Joan31, Holme Susanne31, Kjøeller Morten31, Lund Jens31, Perko Mario31, Sander Kare31, Smerup Morten31, Thiis Jens Juel31, Thyregod Hans Gustav31, Monnin Kathryn31, Popelas Lori31, Slyman Martha31, Grewal Kanny31, Matros Todd31, Richards David31, Watson Daniel31, Yakubov Steven31, Arshi Arash31, Blossom Geoffrey31, Chapekis Anthony31, Duff Steven31, Hicks William31, Holland Stephanie31, Kander Nathan Howard31, Lyons Jefferson31, Mejilla Jennifer31, Reese Brenda31, Sanchez Carlos31, Vora Nirav31, Erwin Sheila31, Hall Jamie31, Hayes Natalie31, King Dana31, Miller Margie31, Main Michael31, Allen Keith31, Chhatriwalla Adnan31, Aggarwal Sanjeev31, Borkon Michael31, Boutwell Christine31, Cohen David31, Davis J. Russell31, Grantham Aaron31, Magalski Anthony31, Olds Karin31, Buchanan Tiffany31, Daniel Misty31, Estrada Katrina31, Hollen Matthew31, Jensen Ann31, Kennen Jada31, Bechis Mary31, Hu Stephen31, Rubenson David31, Teirstein Paul31, Tyner Jeffrey31, Ahmad Daniel31, Atri Prashant31, Azarbal Farnaz31, Brewster Scot31, Brown Christopher31, Foley T. Raymond31, Groves Elliott31, Hanna Nicholas31, Kalafut Mary31, Levisman Jeffrey31, Mellinger Douglas31, Odunukan Olufunso31, Ong Daniel31, Oyama Jared31, Panguluri Praveen31, Patel Aalok31, Raney Aidan31, Rao Suraj31, Schultz Jason31, Sharma Alok31, Stinis Curtiss31, Thompson Caleb31, Wadia Subeer31, Walsh Joseph31, White Jeremy31, Purrington Elizabeth31, Zulick Chelle31, Murillo Jaime31, Mahoney Paul31, Newton Joseph31, Rich Jeffrey31, Bagameri Gabor31, Cohen Daniel31, Dimeling George31, Jordan Grace31, Mistry Neville31, Philpott Jonathan31, Sirak John31, Sourbeer Sarah31, Talreja Deepak31, Zweifler Richard31, Helm Elizabeth31, Postema Karen31, Van Over Elizabeth31, Chilton Dale31, Mitchell Lou31, Heiser John31, Merhi William31, Berkompas Duane31, Fanning Justin31, Khan Muhib31, Leung Wai Sang Stephane31, Omran Kaskar31, Patzelt Lawrence31, Rai Vivek31, Thoits Timothy31, Vijayappa Madhu31, Kasle Margie31, Trautman Leigh31, Dash Rajiv31, Liang David31, Fischbein Michael31, Miller Craig31, Yeung Alan31, Fearon William31, George Paul31, Speight Martina31, Tai Waimai Amy31, Albersen Inke31, Bras Rebecca Gornelda31, Feirabend Conny31, Helwig-Vernooij Johanna Catharina31, Kranen Gerda31, Oostveen Manfred31, Rost Ilona31, van Deutekom Inge31, van Weelden Atie31, Heijmen Robin31, ten Berg Jurriën31, Bosschaert Mike Arnoud Ramon31, de Kroon Thomas L.31, Hilkens Pieter H.E.31, Mast Eliza G.31, Rensing Bernard31, Schonewille W.J.31, van den Akker Alberta Nelina31, Haag Elizabeth31, Jennings Joan31, Krug Patricia31, Santiago Lyn31, Seth Sonika31, Dimsuyu Nellia31, Mihalatos Dennis31, Petrossian George31, Robinson Newell31, Bercow Neil31, Berke Andrew31, Deutsch Ezra31, Stevens Perry31, Brown Sue31, Dos Santos Jardim Victor31, Radford Nicole31, Sookhoo Venessa31, Kyereme Kojo31, Punzalan Rachel31, Reynolds Rebecca31, Sculeany Bogdan31, Sharma Rakesh31, Stuart Amanda31, Brecker Stephen31, Jahangiri Marjan31, Alassa Aiman31, Chandrasekaran Venkatachalam31, Clarke Brian31, Dowling Cameron31, Moynihan Barry31, Roy D.31, Sarsam Mazin31, Bess Renee31, Henkel Megan31, Herbert Natalie31, Cohen Gerald31, Batra Sanjay31, Davis Thomas31, Aboukasm Amer31, Cullis Paul31, LaLonde Thomas31, Martin James31, Yamasaki Hiroshi31, Burkert Marylynn31, Kingma Barbara31, Wheatley Jessica31, Segar Douglas31, Heimansohn David31, Hermiller James31, Ball Michael31, Elsner Gregory31, Hanan Scott31, Moainie Sina31, Nukes Theodore31, Reibold Patrick31, Robison Robert31, Salerno Christopher31, Sampson Andrew31, Walts Peter31, Wandel Emily31, Li Mary31, Sarker Sulagna31, Ahmed Shaheeda31, Fremes Stephen31, Radhakrishnan Sam31, Arbel Yaron31, Christakis George31, Cohen Gideon31, Czarnecki Andrew31, Elbaz-Greener Gabby31, Feld Yair31, Hopyan Julia31, Komatsu Ikki31, McCraig Kathleen31, Shuvy Menashe31, Toma Jonathan31, Vincenzo Basile31, Wheeler Cindi31, Wijeysundera Harindra31, Wolff Rafael31, Beck Pamela31, Cabral Donna31, DaCosta Christine31, Hudson Laura31, Pastie Michelle31, Abrahams Nicole31, Altamar Ingrid31, Buitrago Mike31, Cassman Gabrielle31, Leibovici Zvi31, Nelson Ana31, Recchia Kelly31, Robbins Gillian31, Studor Kelly31, Bethea Brian31, Beyer Erik31, Evans Sharron31, Goodis Caleene31, Malek Ali31, Mueller-Kronast Nils31, Pan Hao31, Pantoja Claudia31, Ramos Angelica31, Wells Channing31, Youngblood Colten31, Snelus Patricia31, Gopal Deepika31, Jackson Kristie31, Brown David31, Ryan William31, Brinkman William31, Gopal Ambarish31, Harrington Katherine31, Mack Michael31, Nosnik Pedro31, Potluri Srinivasa31, Smith Robert31, Szerlip Molly31, Blaylock Candice31, Brinegar Patricia31, Canter Laura31, Green LaShawna31, Green Lisa31, Hazen Pamela31, Jacobs Amber31, Khan Saba31, Ludwig Sheryl31, Mata Mary31, Moore Tammara31, Underwood Carol31, Faza Nadeen31, Little Stephen31, Nagueh Sherif31, Kleiman Neal31, Reardon Michael31, Albright Kimberly31, Atkins Marvin31, Barker Colin31, Bledsoe Donald31, Chiu David31, Goel Sachin31, Gray Tiffany31, Imperial-Aubin 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M.31, Jander Nikolaus31, Beyersdorf Friedhelm31, Neumann Franz-Josef31, Büttner Heinz Joachim31, Comberg Thomas31, Diab Nawras31, Gick Michael31, Günkel Ludwig31, Pingpoh Clarence31, Rothe H. 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Affiliation:
1. Department of Interventional Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands 2. Department of Interventional Cardiology, University of Michigan, Ann Arbor 3. Department of Cardiac Surgery, University of Michigan, Ann Arbor 4. Department of Cardiology, The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark 5. Department of Interventional Cardiology, University of Bonn, Bonn, Germany 6. Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland 7. Department of Interventional Cardiology, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania 8. Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania 9. Department of Interventional Cardiology, Spectrum Health, Grand Rapids, Michigan 10. Department of Cardiothoracic Surgery, Spectrum Health, Grand Rapids, Michigan 11. Department of Interventional Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas 12. Department of Cardiothoracic Surgery, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas 13. Department of Interventional Cardiology, University of Pittsburgh, Pittsburgh, Pennsylvania 14. Now with Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore 15. Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 16. Department of Interventional Cardiology, Cedars-Sinai Medical Center, Los Angeles, California 17. Department of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, California 18. Department of Interventional Cardiology, Ohio State University Wexner Medical Center, Columbus 19. Now with Mayo Clinic, Rochester, Minnesota 20. Department of Cardiovascular Surgery, Ohio State University Wexner Medical Center, Columbus 21. Department of Interventional Cardiology, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York 22. Department of Cardiothoracic Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York 23. Department of Interventional Cardiology, OhioHealth Riverside Methodist Hospital, Columbus 24. Now with National University of Ireland, Galway, Ireland 25. Department of Cardiac Surgery, German Heart Center, Munich, Germany 26. Department of Interventional Cardiology, McGill University Health Centre, Montreal, Quebec, Canada 27. Department of Interventional Cardiology and Cardiac Surgery, Langone-New York University, New York 28. Echocardiography Core Laboratory, Mayo Clinic, Rochester, Minnesota 29. Department of Cardiovascular Surgery, Mount Sinai Health System, New York, New York 30. Clinical Research, Medtronic, Minneapolis, Minnesota 31. for the SURTAVI Trial Investigators
Abstract
ImportanceIn patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longer-term clinical and hemodynamic outcomes in these patients are limited.ObjectiveTo report prespecified secondary 5-year outcomes from the Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI) randomized clinical trial.Design, Setting, and ParticipantsSURTAVI is a prospective randomized, unblinded clinical trial. Randomization was stratified by investigational site and need for revascularization determined by the local heart teams. Patients with severe aortic valve stenosis deemed to be at intermediate risk of 30-day surgical mortality were enrolled at 87 centers from June 19, 2012, to June 30, 2016, in Europe and North America. Analysis took place between August and October 2021.InterventionPatients were randomized to TAVR with a self-expanding, supra-annular transcatheter or a surgical bioprosthesis.Main Outcomes and MeasuresThe prespecified secondary end points of death or disabling stroke and other adverse events and hemodynamic findings at 5 years. An independent clinical event committee adjudicated all serious adverse events and an independent echocardiographic core laboratory evaluated all echocardiograms at 5 years.ResultsA total of 1660 individuals underwent an attempted TAVR (n = 864) or surgical (n = 796) procedure. The mean (SD) age was 79.8 (6.2) years, 724 (43.6%) were female, and the mean (SD) Society of Thoracic Surgery Predicted Risk of Mortality score was 4.5% (1.6%). At 5 years, the rates of death or disabling stroke were similar (TAVR, 31.3% vs surgery, 30.8%; hazard ratio, 1.02 [95% CI, 0.85-1.22]; P = .85). Transprosthetic gradients remained lower (mean [SD], 8.6 [5.5] mm Hg vs 11.2 [6.0] mm Hg; P < .001) and aortic valve areas were higher (mean [SD], 2.2 [0.7] cm2 vs 1.8 [0.6] cm2; P < .001) with TAVR vs surgery. More patients had moderate/severe paravalvular leak with TAVR than surgery (11 [3.0%] vs 2 [0.7%]; risk difference, 2.37% [95% CI, 0.17%- 4.85%]; P = .05). New pacemaker implantation rates were higher for TAVR than surgery at 5 years (289 [39.1%] vs 94 [15.1%]; hazard ratio, 3.30 [95% CI, 2.61-4.17]; log-rank P < .001), as were valve reintervention rates (27 [3.5%] vs 11 [1.9%]; hazard ratio, 2.21 [95% CI, 1.10-4.45]; log-rank P = .02), although between 2 and 5 years only 6 patients who underwent TAVR and 7 who underwent surgery required a reintervention.Conclusions and RelevanceAmong intermediate-risk patients with symptomatic severe aortic stenosis, major clinical outcomes at 5 years were similar for TAVR and surgery. TAVR was associated with superior hemodynamic valve performance but also with more paravalvular leak and valve reinterventions.
Publisher
American Medical Association (AMA)
Subject
Cardiology and Cardiovascular Medicine
Cited by
66 articles.
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