1. Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa
2. Hatter Institute for Cardiovascular Diseases Research in Africa and Cape Heart Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa
3. Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada
4. Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada
5. Department of Pathology and Molecular Medicine, McMaster University, Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada
6. Rheumatic Heart Disease Clinic, Windhoek Central Hospital, Ministry of Health and Social Services, Windhoek, Republic of Namibia
7. Cardiology Department of Medicine, Kenyatta National Hospital, University of Nairobi, Nairobi, Kenya
8. Uganda Heart Institute, Kampala, Uganda
9. Faculty of Medicine, Eduardo Mondlane University/Nucleo de Investigaçao, Departamento de Medicina, Hospital Central de Maputo, Maputo, Mozambique
10. Instituto Nacional de Saúde Ministério da Saúde, Maputo, Moçambique
11. Emergency Department, World Health Organization Mozambique, Maputo, Mozambique
12. Department of Paediatrics and Child Health, University Teaching Hospital–Children’s Hospital, University of Zambia, Lusaka, Zambia
13. Department of Cardiothoracic Surgery, Alshaab Teaching Hospital, Alazhari Health Research Center, Alzaiem Alazhari University, Khartoum, Sudan
14. Department of Paediatrics, Jos University Teaching Hospital and University of Jos, Jos, Plateau State Nigeria
15. Division of Paediatric Cardiology, Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital and University of Cape Town, South Africa
16. Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
17. Department of Pathology, University of Cape Town, Cape Town, South Africa
18. Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
19. Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom
20. Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, United Kingdom
21. Manchester University National Health Service Foundation Trust, Manchester Academic Health Science CentreManchester, United Kingdom
22. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton Ontario, Canada