Age-Adjusted Survival Extrapolations—Results May Differ From Those Generated by the Weibull Model

Author:

Messori Andrea1,Mengato Daniele2,Chiumente Marco3

Affiliation:

1. HTA Unit, Regione Toscana and ESTAR, Regional Health Service, Firenze, Italy

2. Hospital Pharmacy Department, Bolzano Central Hospital, Bolzano, Italy

3. Scientific Direction, Italian Society for Clinical Pharmacy and Therapeutics, Milan, Italy

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

Reference5 articles.

1. Dapagliflozin in patients with heart failure and reduced ejection fraction.;McMurray;N Engl J Med,2019

2. Extrapolating long-term event-free and overall survival with dapagliflozin in patients with heart failure and reduced ejection fraction: an exploratory analysis of a phase 3 randomized clinical trial.;Docherty;JAMA Cardiol,2021

3. Estimating the lifetime benefits of treatments for heart failure.;Ferreira;JACC Heart Fail,2020

4. The restricted mean survival time as a replacement for the hazard ratio and the number needed to treat in long-term studies.;Messori;ESC Heart Fail,2021

5. Messori? A. Weibull extrapolation of survival data: analysis of 36 articles published in PubMed. Open Science Framework. Preprint posted online July 31, 2021. Accessed August 2, 2021. https://osf.io/3bh48/

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