Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events

Author:

Zhang Yiyi1,Pletcher Mark J.2,Vittinghoff Eric2,Clemons Autumn M.3,Jacobs David R.4,Allen Norrina B.5,Alonso Alvaro6,Bellows Brandon K.1,Oelsner Elizabeth C.1,Zeki Al Hazzouri Adina3,Kazi Dhruv S.7,de Ferranti Sarah D.8,Moran Andrew E.1

Affiliation:

1. Division of General Medicine, Columbia University Medical Center, New York, New York

2. Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco

3. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York

4. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis

5. Department of Preventive Medicine, Northwestern University, Chicago, Illinois

6. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia

7. Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts

8. Department of Cardiology, Boston Children’s Hospital, Boston, Massachusetts

Publisher

American Medical Association (AMA)

Subject

Cardiology and Cardiovascular Medicine

Reference21 articles.

1. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.;Grundy;Circulation,2019

2. Impact of lipids on cardiovascular health: JACC health promotion series.;Ference;J Am Coll Cardiol,2018

3. Trajectories of blood lipid concentrations over the adult life course and risk of cardiovascular disease and all-cause mortality: observations from the Framingham Study over 35 years.;Duncan;J Am Heart Assoc,2019

4. Associations of blood pressure and cholesterol levels during young adulthood with later cardiovascular events.;Zhang;J Am Coll Cardiol,2019

5. Time course of LDL cholesterol exposure and cardiovascular disease event risk.;Domanski;J Am Coll Cardiol,2020

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