Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials-Reference-Cited by-同舟云学术

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Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials

Published:2020-09-01 Issue:9 Volume:77 Page:1132
ISSN:2168-6149
Container-title:JAMA Neurology
language:en
Short-container-title:JAMA Neurol

Author:

Kappos Ludwig¹,Wolinsky Jerry S.²,Giovannoni Gavin³,Arnold Douglas L.⁴⁵,Wang Qing⁶,Bernasconi Corrado⁶,Model Fabian⁶,Koendgen Harold⁶,Manfrini Marianna⁶,Belachew Shibeshih⁶⁷,Hauser Stephen L.⁸

Affiliation:

1. University Hospital Basel, University of Basel, Basel, Switzerland

2. McGovern Medical School, The University of Texas Health Science Center at Houston, Houston

3. Queen Mary University of London, London, United Kingdom

4. McGill University, Montreal, Quebec, Canada

5. NeuroRx Research, Montreal, Quebec, Canada

6. F. Hoffmann–La Roche Ltd, Basel, Switzerland

7. Now with Biogen, Cambridge, Massachusetts

8. Weill Institute for Neurosciences, University of California, San Francisco, San Francisco

Publisher

American Medical Association (AMA)

Subject

Clinical Neurology

Link

https://jamanetwork.com/journals/jamaneurology/articlepdf/2766801/jamaneurology_kappos_2020_oi_200035_1598965180.36957.pdf

Reference26 articles.

1. Defining the clinical course of multiple sclerosis: the 2013 revisions.;Lublin;Neurology,2014

2. Relationship between early clinical characteristics and long term disability outcomes: 16 year cohort study (follow-up) of the pivotal interferon ß-1b trial in multiple sclerosis.;Goodin;J Neurol Neurosurg Psychiatry,2012

3. Predictors of long-term disability accrual in relapse-onset multiple sclerosis.;Jokubaitis;Ann Neurol,2016

4. Worsening of disability caused by relapses in multiple sclerosis: a different approach.;Koch-Henriksen;Mult Scler Relat Disord,2019

5. Long-term evolution of multiple sclerosis disability in the treatment era.;Cree;Ann Neurol,2016

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4. MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial;Trials;2024-09-11

5. Assessing disease progression and treatment response in progressive multiple sclerosis;Nature Reviews Neurology;2024-09-09

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