Study the subchronic toxicity of the drug Dantinorm Baby-Reference-Cited by-同舟云学术

Study the subchronic toxicity of the drug Dantinorm Baby

Published:2021-06-22 Issue:3 Volume: Page:52-60
ISSN:2686-8830
Container-title:Pharmacokinetics and Pharmacodynamics
language:
Short-container-title:Fk&Fd

Author:

Sorokina A. V.¹^ORCID,Alekseeva S. V.¹^ORCID,Miroshkina I. A.¹^ORCID,Kachalov K. S.²,Zaharov A. D.¹,Alekseev I. V.²,Lapizkaya A. S.³

Affiliation:

1. FSBI «Zakusov Institute of Pharmacology»

2. FSBI «Zakusov Institute of Pharmacology»; Moscow medical university «Reaviz»

3. Gabricheysky Institute of Epidemiology and Microbiology

Abstract

Presents results of a study of subchronic toxicity of homeopathic drug Dantinorm Baby in finished dosage form. The drug in the form of a ready solution was administered daily orally for one month to outbred rats Infanta and chinchilla rabbits at a dose of 0.3 ml/kg, corresponding to the therapeutic, and 3 ml/kg, exceeding the therapeutic dose 10 times. Clinical, laboratory and histopathological studies performed in accordance with the General Protocol, showed no toxic effects of homeopathic preparation of Dantinorm Baby. The totality of the obtained data of the subchronic experiment indicates that there are no obstacles to the clinical study of the drug Dantinorm Baby in the range of therapeutic dosages.

Publisher

Publishing House OKI

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

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1. Therapeutic efficacy and safety of the use of the homeopathic preparation during teething in children;Meditsinskiy sovet = Medical Council;2023-03-11