Absolute bioavailability of a substance with cardioprotective activity (ALM-802) in rats

Author:

Kolyvanov G. B.1ORCID,Bochkov P. O.1ORCID,Litvin A. A.1ORCID,Shevchenko R. V.1ORCID,Podolko A. L.1ORCID,Zherdev V. P.1

Affiliation:

1. FSBI “Zakusov Institute of Pharmacology”

Abstract

The pharmacokinetics of a new potential cardioprotective agent ALM-802 was studied in rats after single intravenous and intragastric administration at doses of 10 and 100 mg/kg, respectively. The absolute bioavailability was 4.45 %, which indicates the potential for the development of a dosage form for oral administration

Publisher

Publishing House OKI

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

Reference3 articles.

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1. Disribution kinetics of cardioprotector ALM-802 in rat organs and tissues;Pharmacokinetics and Pharmacodynamics;2022-07-06

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