Affiliation:
1. FSBEI HE First St. Petersburg State Medical University named after I. P. Pavlov
2. FSBEI HE First St. Petersburg State Medical University named after I. P. Pavlov; FSBI National Research Center of Oncology named after N. N. Petrov of the Ministry of Health of Russia
Abstract
For many reasons randomized clinical trials today can»t cope with the tasks set by modern health care, which was clearly demonstrated by the COVID-19 pandemic. This gave new impetus to the development of the RWD / RWE. It became obviously that in cases of impossibility, unethical and other reasons, new methods for obtaining high-quality evidence may be effectively used, and later can be used by decision-makers and organizations engaged in the assessment of health technologies.