Short-Chain Fatty Acids Activate AMP-Activated Protein Kinase and Ameliorate Ethanol-Induced Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers

Author:

Elamin Elhaseen E.123,Masclee Ad A.123,Dekker Jan14,Pieters Harm-Jan23,Jonkers Daisy M.123

Affiliation:

1. Top Institute Food and Nutrition, Wageningen, The Netherlands

2. Department of Internal Medicine, Division of Gastroenterology–Hepatology, and

3. School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands

4. Department of Animal Sciences, Wageningen University, Wageningen, The Netherlands

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference56 articles.

1. The effects of alcohol consumption upon the gastrointestinal tract;Bujanda;Am J Gastroenterol,2000

2. Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms;Banan;J Pharmacol Exp Ther,1999

3. Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model;Elamin;PLoS One,2012

4. The differing effects of acute and chronic alcohol on gastric and intestinal permeability;Keshavarzian;Am J Gastroenterol,1994

5. The leaky gut of alcoholism: possible route of entry for toxic compounds;Bjarnason;Lancet,1984

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